Protein Info for Atu1522 in Agrobacterium fabrum C58

Annotation: transcriptional regulator, LacI family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 339 PF00356: LacI" amino acids 10 to 55 (46 residues), 37.4 bits, see alignment 2.7e-13 PF00532: Peripla_BP_1" amino acids 81 to 319 (239 residues), 53.3 bits, see alignment E=4.5e-18 PF13377: Peripla_BP_3" amino acids 177 to 322 (146 residues), 56 bits, see alignment E=8.4e-19

Best Hits

KEGG orthology group: K02529, LacI family transcriptional regulator (inferred from 100% identity to atu:Atu1522)

Predicted SEED Role

"Predicted transcriptional regulators"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7CZ24 at UniProt or InterPro

Protein Sequence (339 amino acids)

>Atu1522 transcriptional regulator, LacI family (Agrobacterium fabrum C58)
MPSAMGGRPTLKTIAYMTGLGITTVSRALKDAPDIGAETKERVRLIARQIGYQPNRAGVR
LRTGKTNVIALVLSVDEELMGFTSQMVFGITEVLSTTQYHLVVTPHIHAKDSMVPIRYIL
ETGSADGVIISKIEPNDPRVRFMTERNMPFVTHGRSDMGIEHAFHDFDNEAYAYEAVERL
AQCGRKRIAVIVPPSRFSFHDHARKGFNRGIRDFGLTEFPIDAVTIETPLEKIRDFGQRL
MQSSDRPDGIVSISGSSTIALVAGFEAAGVKIGEDVDIVSKQSAEFLNWIKPQIHTVNED
IKLAGRELAKALLARINGEAAETLQSISGPVWSSMAPKP