Protein Info for Atu1507 in Agrobacterium fabrum C58

Annotation: DNA gyrase subunit A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 906 TIGR01063: DNA gyrase, A subunit" amino acids 1 to 875 (875 residues), 1116.2 bits, see alignment E=0 PF00521: DNA_topoisoIV" amino acids 16 to 481 (466 residues), 541.5 bits, see alignment E=1.5e-166 PF03989: DNA_gyraseA_C" amino acids 513 to 560 (48 residues), 47.1 bits, see alignment 1.3e-16 amino acids 565 to 612 (48 residues), 19.6 bits, see alignment 5.1e-08 amino acids 623 to 667 (45 residues), 27.6 bits, see alignment 1.6e-10 amino acids 671 to 718 (48 residues), 45 bits, see alignment 5.9e-16 amino acids 776 to 824 (49 residues), 35 bits, see alignment 7.5e-13 amino acids 828 to 875 (48 residues), 42.2 bits, see alignment 4.5e-15

Best Hits

Swiss-Prot: 56% identical to GYRA_GRABC: DNA gyrase subunit A (gyrA) from Granulibacter bethesdensis (strain ATCC BAA-1260 / CGDNIH1)

KEGG orthology group: K02469, DNA gyrase subunit A [EC: 5.99.1.3] (inferred from 100% identity to atu:Atu1507)

Predicted SEED Role

"DNA gyrase subunit A (EC 5.99.1.3)" in subsystem DNA topoisomerases, Type II, ATP-dependent or Resistance to fluoroquinolones (EC 5.99.1.3)

Isozymes

Compare fitness of predicted isozymes for: 5.99.1.3

Use Curated BLAST to search for 5.99.1.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7CZ37 at UniProt or InterPro

Protein Sequence (906 amino acids)

>Atu1507 DNA gyrase subunit A (Agrobacterium fabrum C58)
MQRSYLDYAMSVIVSRALPDVRDGLKPVHRRILYGMSELGIDWNKKYVKCARVTGDVMGK
FHPHGNSAIYDALARMAQDWSLRLPLIDGQGNFGSIDGDPPAAERYTECRLEKAAHSLLD
DLDKETVDFRDNYDGTLQEPVVVPAKFPNLLVNGAGGIAVGMATNIPPHNLSEVIDGCVA
LIENPAIELPEMMQIIPGPDFPTGALIMGRSGIRSAYETGRGSVIMRGVATIEPMRGDRE
QIIITEVPYQVNKASMIEKMAELVKEKRIEGISDLRDESDRQGYRVVIELKRDANAEVIL
NQLYRYTPLQTSFGCNMVALNGGKPEQMTLLDMLRAFVSFREDVVSRRTKYLLRKARDRA
HVLVGLAISVANIDEVIRVIRHAPDPASAREQLMTRRWPAQDVESLIRLIDDPRHRINED
GTYNLSEEQARAILELRLARLTALGRDEIGDELNKIGAEISEYLDILSSRVRIQQIVKDE
LVSIRDEFGTPRRSQIVEGGPDMDDEDLIAREDMVVTVSHLGYIKRVPLTTYRAQRRGGK
GRSGMATRDEDFVNRLFVANTHTPVLFFSSRGIVYKEKVWRLPIGTPQSKGKALINMLPL
EPGERITTIMPLPEDETAWETLDVMFSTTRGTVRRNKLGDFVQVNRNGKIAMKLDEEGDE
ILSVETCTDRDDVLLTTALGQCIRFPVDDVRVFAGRNSVGVRGINMAEGDRIISMTIVGH
VEAEPWERAAYLKRSATERRAAGVDEEDIALVGEEVTEEGELSEERYQELKAREEFVLTV
SVKGFGKRSSSYDFRTSGRGGKGIRATDTAKTNEIGELVAAFPVEEGDQIMLVSDGGQLI
RVPVNGIRIASRATKGVTIFSTAKDEKVVSVERINEPEGDDEAENGNDDEADDNLPDAPE
APESEA