Protein Info for Atu1398 in Agrobacterium fabrum C58

Annotation: ABC transporter, membrane spanning protein (amino acid)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 234 transmembrane" amino acids 20 to 45 (26 residues), see Phobius details amino acids 66 to 86 (21 residues), see Phobius details amino acids 92 to 109 (18 residues), see Phobius details amino acids 148 to 170 (23 residues), see Phobius details amino acids 190 to 217 (28 residues), see Phobius details TIGR01726: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family" amino acids 15 to 111 (97 residues), 89 bits, see alignment E=1.2e-29 PF00528: BPD_transp_1" amino acids 32 to 214 (183 residues), 62.1 bits, see alignment E=3e-21

Best Hits

Swiss-Prot: 31% identical to YECS_ECOL6: L-cystine transport system permease protein YecS (yecS) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K02029, polar amino acid transport system permease protein (inferred from 100% identity to atu:Atu1398)

MetaCyc: 31% identical to cystine ABC transporter membrane subunit (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-290 [EC: 7.4.2.12]; 7.4.2.12 [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]

Predicted SEED Role

"polar amino acid ABC transporter, inner membrane subunit"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7CZC5 at UniProt or InterPro

Protein Sequence (234 amino acids)

>Atu1398 ABC transporter, membrane spanning protein (amino acid) (Agrobacterium fabrum C58)
MNFSLHFEAVFAESDLIWRGILLTIGLSATAIVLGTMIAVALVAMRSLGNGTIRFCVDSY
VELLRNTPFLVQLFMVFFGLPLVGFRMSGTQAALFAMTLNLSAYATEIIRAGVESIHRSQ
VEAGLSLSLSRLQVFRYVVMKPAFAKIWPALSSQFVLMLLASSICSFISVPELSGAASII
EQRTFRSFETYIVVTVIYLLLALALKIILAWFGHWLFRRRVKVFSPMTVQEGIA