Protein Info for Atu1397 in Agrobacterium fabrum C58

Annotation: ABC transporter, membrane spanning protein (amino acid)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 217 transmembrane" amino acids 16 to 40 (25 residues), see Phobius details amino acids 52 to 73 (22 residues), see Phobius details amino acids 84 to 103 (20 residues), see Phobius details amino acids 146 to 166 (21 residues), see Phobius details amino acids 182 to 201 (20 residues), see Phobius details TIGR01726: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family" amino acids 10 to 106 (97 residues), 85 bits, see alignment E=2.1e-28 PF00528: BPD_transp_1" amino acids 31 to 209 (179 residues), 67.3 bits, see alignment E=7.8e-23

Best Hits

Swiss-Prot: 40% identical to YECS_SHIFL: L-cystine transport system permease protein YecS (yecS) from Shigella flexneri

KEGG orthology group: K02029, polar amino acid transport system permease protein (inferred from 100% identity to atu:Atu1397)

MetaCyc: 40% identical to cystine ABC transporter membrane subunit (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-290 [EC: 7.4.2.12]; 7.4.2.12 [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]

Predicted SEED Role

"Ribose ABC transport system, permease protein RbsC (TC 3.A.1.2.1)" in subsystem D-ribose utilization (TC 3.A.1.2.1)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CJ50 at UniProt or InterPro

Protein Sequence (217 amino acids)

>Atu1397 ABC transporter, membrane spanning protein (amino acid) (Agrobacterium fabrum C58)
MSTFGWPEFLFLLRGAGWSIVLTAIAFSIGSLTGGFFAIMRLSQYGSVRNVAAGYITVIQ
SIPVLMILFMSYYGLTLFGFEIPPLLAASVSLSVYVSAYLAEIWRGSIQAVPKPQWEASA
SLALTRFQQYRYVILPQALRLSLPPTVGFLVQLVKNTSIVSVVGFVELSRAGQLVNNATF
RPFQVFFVVALLYFAICFPLSRLSRHLERVLHVGRNN