Protein Info for Atu1390 in Agrobacterium fabrum C58

Annotation: ABC transporter, membrane spanning protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 219 transmembrane" amino acids 20 to 41 (22 residues), see Phobius details amino acids 55 to 79 (25 residues), see Phobius details amino acids 85 to 105 (21 residues), see Phobius details amino acids 142 to 166 (25 residues), see Phobius details amino acids 183 to 201 (19 residues), see Phobius details TIGR01726: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family" amino acids 11 to 107 (97 residues), 87.4 bits, see alignment E=3.7e-29 PF00528: BPD_transp_1" amino acids 40 to 210 (171 residues), 55.6 bits, see alignment E=2.9e-19

Best Hits

Swiss-Prot: 38% identical to YECS_ECOL6: L-cystine transport system permease protein YecS (yecS) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K02029, polar amino acid transport system permease protein (inferred from 100% identity to atu:Atu1390)

MetaCyc: 38% identical to cystine ABC transporter membrane subunit (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-290 [EC: 7.4.2.12]; 7.4.2.12 [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]

Predicted SEED Role

"Putative amino acid ABC transporter, permease protein"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CJ55 at UniProt or InterPro

Protein Sequence (219 amino acids)

>Atu1390 ABC transporter, membrane spanning protein (Agrobacterium fabrum C58)
MIEFSTWDILRNLLLATRWTVLLSLVSFAGGGLVALLLLFMRISRKKSMRVFARYYVELF
QGTPLLMQLFIAFFGLGLVGIDVPAWLAAGLTLILWAAAFLTEIWRGCVESVAKGQWEAS
ASLAMGRLQQMRYVILPQAMRVAIPPTVGFFVQVIKGTAVTSIIGFVELSKAGTVVTNAT
FQPFTVYGLVALIYFALCWPLSKSSQILERKLNVAHRNH