Protein Info for Atu1379 in Agrobacterium fabrum C58

Annotation: phosphatidate cytidylyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 277 transmembrane" amino acids 12 to 43 (32 residues), see Phobius details amino acids 60 to 76 (17 residues), see Phobius details amino acids 80 to 97 (18 residues), see Phobius details amino acids 103 to 122 (20 residues), see Phobius details amino acids 128 to 150 (23 residues), see Phobius details amino acids 170 to 190 (21 residues), see Phobius details amino acids 196 to 215 (20 residues), see Phobius details amino acids 244 to 262 (19 residues), see Phobius details PF01148: CTP_transf_1" amino acids 6 to 256 (251 residues), 187.9 bits, see alignment E=1.7e-59

Best Hits

KEGG orthology group: K00981, phosphatidate cytidylyltransferase [EC: 2.7.7.41] (inferred from 100% identity to atu:Atu1379)

Predicted SEED Role

"Phosphatidate cytidylyltransferase (EC 2.7.7.41)" in subsystem Glycerolipid and Glycerophospholipid Metabolism in Bacteria (EC 2.7.7.41)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.7.41

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CJ62 at UniProt or InterPro

Protein Sequence (277 amino acids)

>Atu1379 phosphatidate cytidylyltransferase (Agrobacterium fabrum C58)
MSRELKLRIVSAIVMAAVILAATWYGGILFRIVAGLLAILIYYEWSTITRMSETNSTGNA
WGWFAVAVIAGNTIFGESSLDLPLLSGFTLTAALFPVLRGKNWWLVGGIFYAGLSGISLA
AIRGDELAGFASILFIFAVVWSTDILAYFVGRAIGGPKLAPSISPGKTWSGAVGGAVAAV
IGGAAVSMAYHGRISLLLVGLALVLSVFSQIGDLFESFVKRRFQVKDSSHLIPGHGGFMD
RVDGLVFACFTVFLIAFVHAAATGDVPGSGGGLLPGF