Protein Info for Atu1317 in Agrobacterium fabrum C58

Annotation: metal dependent hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 366 PF13483: Lactamase_B_3" amino acids 134 to 330 (197 residues), 70.5 bits, see alignment E=2.5e-23 PF00753: Lactamase_B" amino acids 136 to 224 (89 residues), 44.4 bits, see alignment E=3e-15 PF12706: Lactamase_B_2" amino acids 151 to 314 (164 residues), 67.9 bits, see alignment E=1.5e-22

Best Hits

KEGG orthology group: None (inferred from 100% identity to atu:Atu1317)

Predicted SEED Role

"metallo-beta-lactamase family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (366 amino acids)

>Atu1317 metal dependent hydrolase (Agrobacterium fabrum C58)
MLPLSFTDEFGAQHQTLDRIMPAIDLFGIVGQADRLDDGALLDDRVGALDLQVLDQCHGI
AVFKHIAGGIAHFLCTGCLGGQFGSRPPFAARFVIHVIVIIRGHCRLSEISVVRLFRPSY
VIIYRQYKGELPMKLTWLGHSAFRLENGSAKILIDPFFTGNPGFAGQDGKSAAEGITHIL
LTHGHGDHVGDTVQLARETGATVLANADLAAWLSAKGVAKVDMGNTGGTVHFDGFSVTFT
NALHSSAQITEDGVSHSLGNANGLMLHFEDGPAVYHMGDTDIFSDMKLINELHQPDIGLV
PIGDRFTMGGAVAALACQRFFKFQNVIPCHYGSFPIIDQTPDKFVAGMEGAEARVHTPKA
GDTLSF