Protein Info for Atu1310 in Agrobacterium fabrum C58

Annotation: acyl-CoA dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 PF18158: AidB_N" amino acids 15 to 172 (158 residues), 171.3 bits, see alignment E=4.1e-54 PF02770: Acyl-CoA_dh_M" amino acids 187 to 280 (94 residues), 61.5 bits, see alignment E=1.8e-20 PF00441: Acyl-CoA_dh_1" amino acids 290 to 445 (156 residues), 106.4 bits, see alignment E=3.9e-34 PF08028: Acyl-CoA_dh_2" amino acids 308 to 430 (123 residues), 46 bits, see alignment E=1.6e-15 PF22924: ACOX_C_alpha1" amino acids 373 to 445 (73 residues), 28.5 bits, see alignment E=3.2e-10

Best Hits

KEGG orthology group: K09456, putative acyl-CoA dehydrogenase (inferred from 100% identity to atu:Atu1310)

Predicted SEED Role

"Acyl-CoA dehydrogenase (EC 1.3.8.7)" (EC 1.3.8.7)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 1.3.8.7

Use Curated BLAST to search for 1.3.8.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CJ90 at UniProt or InterPro

Protein Sequence (550 amino acids)

>Atu1310 acyl-CoA dehydrogenase (Agrobacterium fabrum C58)
MTQNSRTEETLAELNQPSLWSGINAYRSDPLIVDLTSGLSRNLRDEYDQLGRYVTSHEAQ
ELARMANQGVPQLHTHGPRGERLDQVEFHPAWHALMRRSMSSGLHSSVWENSPDTRGSEH
KARATKFYLTSQLEAGHLCPLTMTSASVAAIMTSPRVQKEWMPKILSRKYDSAQKPALQK
TAVTVGMGMTEKQGGTDVRANRTTAERVGEGIYRLSGHKWFLSAPMSDGFVMLAQMGDGM
GCFLVPRYLEDGSKNGLHFQRLKDKLGNRSNASAEVEFTDAFGYLLGDPGSGIRTILDMV
TLTRLDCALASAGMMRASLAEAVHFARGRSVFGKMLVSQPIMTRVLADMALDVAAATALS
FRLATAFDAARNNPAEAAYARVMTPIVKYWCCKIAPALIYEAMECLGGNGYVEERPIARH
YREAPVNAIWEGSGNVMALDVLRVLQRGKDLFDLVFQTLERDLGPAGKKTTDVLRAAIAL
AERDEGAARLLVEQFALAAAAAELCRLGAGKIADAFLETRLAGGWRHTYGMLDSRFDPNY
IIDLLYPPAS