Protein Info for Atu1281 in Agrobacterium fabrum C58

Annotation: NADH ubiquinone oxidoreductase chain L

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 665 transmembrane" amino acids 6 to 24 (19 residues), see Phobius details amino acids 31 to 54 (24 residues), see Phobius details amino acids 86 to 106 (21 residues), see Phobius details amino acids 118 to 135 (18 residues), see Phobius details amino acids 141 to 160 (20 residues), see Phobius details amino acids 181 to 201 (21 residues), see Phobius details amino acids 234 to 255 (22 residues), see Phobius details amino acids 269 to 287 (19 residues), see Phobius details amino acids 299 to 320 (22 residues), see Phobius details amino acids 327 to 349 (23 residues), see Phobius details amino acids 356 to 376 (21 residues), see Phobius details amino acids 396 to 421 (26 residues), see Phobius details amino acids 439 to 462 (24 residues), see Phobius details amino acids 484 to 504 (21 residues), see Phobius details amino acids 541 to 560 (20 residues), see Phobius details amino acids 641 to 661 (21 residues), see Phobius details TIGR01974: proton-translocating NADH-quinone oxidoreductase, chain L" amino acids 2 to 660 (659 residues), 906.8 bits, see alignment E=4.9e-277 PF00662: Proton_antipo_N" amino acids 69 to 119 (51 residues), 81.8 bits, see alignment 4e-27 PF00361: Proton_antipo_M" amino acids 135 to 442 (308 residues), 291.9 bits, see alignment E=8e-91 PF06455: NADH5_C" amino acids 534 to 656 (123 residues), 30.3 bits, see alignment E=4.6e-11

Best Hits

KEGG orthology group: K00341, NADH dehydrogenase I subunit L [EC: 1.6.5.3] (inferred from 100% identity to atu:Atu1281)

Predicted SEED Role

"NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3)" in subsystem Respiratory Complex I (EC 1.6.5.3)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.6.5.3

Use Curated BLAST to search for 1.6.5.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CJA3 at UniProt or InterPro

Protein Sequence (665 amino acids)

>Atu1281 NADH ubiquinone oxidoreductase chain L (Agrobacterium fabrum C58)
MIYKAIVFLPLIGFLIAGLFGRSIGAKASEYVTTGLMIVVAILSWIVFFNVALAHGEPGE
VIKVTVLRWIQSGGIDVEWAFRIDTLTAVMFVVVNTVSTLVHLYSIGYMHHDPHRPRFFA
YLSLFTFAMLMLVTSDNLLQMFFGWEGVGLASYLLIGFWFKKPSASAAAMKAFIVNRVGD
FGFILGISGVFVLFGSINLETVFAAASTYLPAEGAASTGTVINLFGMQLDKANAITGVCL
LLFMGAMGKSAQFLLHTWLPDAMEGPTPVSALIHAATMVTAGVFLVARMSPLFELSPDAL
TVVTLIGAITAFFAATVGLVQNDIKRVIAYSTCSQLGYMFVALGVGAYGAAVFHLFTHAF
FKALLFLCAGSVIHAVDGEQDMRYMGGLRKHIPITFWTMTVGTLALTGVGIPGTMIGFAG
FFSKDVIIESAYASHSVLSGFAFTLLVIAALFTSFYSWRLAFMTFFGKPRASADVMHHVH
ESPMVMLIPLFILTVGAIFAGVLFEGHFFGEEYVEFWKGALFMLPENEILEEFHHVPLWV
KWSPFFAMALGFVTAWYMYIKSPETPKRLAATHRGLYQFLLNKWYFDELYDFLFVRSAKA
LGRFLWKKGDVAVIDHYGPNGIAARVVDVTNRMVRLQSGYLYHYAFAMLIGIAALVTWMM
LGSAL