Protein Info for Atu1243 in Agrobacterium fabrum C58

Annotation: streptomycin resistance protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 281 PF04655: APH_6_hur" amino acids 12 to 259 (248 residues), 200.5 bits, see alignment E=4.7e-63 PF01636: APH" amino acids 76 to 210 (135 residues), 31.7 bits, see alignment E=2e-11 PF03881: Fructosamin_kin" amino acids 155 to 203 (49 residues), 22.4 bits, see alignment 9.9e-09

Best Hits

KEGG orthology group: None (inferred from 100% identity to atu:Atu1243)

Predicted SEED Role

"streptomycin phosphotransferase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CJC3 at UniProt or InterPro

Protein Sequence (281 amino acids)

>Atu1243 streptomycin resistance protein (Agrobacterium fabrum C58)
MISNTPSFPASWNIEAAKRIADTPAGIVYELTRKDGSLAIAKVLKKKVLKDSLRGADFIA
WRAGIGCVELLDQSDNILLMEHAGTETLRDVLFRDGNDDATTEIAAEVLLRYHQPSEQSP
PSSLLTLPLYFESLFRKAEQDRSDGVDSPFVEAARLAQTLIDQQRDIKPLHGDLHHENIM
HSDRGWIIIDPAGLIGDAALDVANMFSNPLDRFDLTRSEARIASMAAIFSRALQRDERLL
LQYAFAYGCLSATWHEEDGNAEERDNELAVAATIKAVLKHF