Protein Info for Atu1215 in Agrobacterium fabrum C58

Annotation: thiosulfate sulfurtransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 473 PF00581: Rhodanese" amino acids 11 to 130 (120 residues), 53.9 bits, see alignment E=2.2e-18 amino acids 165 to 271 (107 residues), 38.8 bits, see alignment E=1.1e-13 PF00583: Acetyltransf_1" amino acids 348 to 448 (101 residues), 25.6 bits, see alignment E=1.3e-09

Best Hits

KEGG orthology group: K01011, thiosulfate/3-mercaptopyruvate sulfurtransferase [EC: 2.8.1.1 2.8.1.2] (inferred from 100% identity to atu:Atu1215)

Predicted SEED Role

"Thiosulfate sulfurtransferase, rhodanese (EC 2.8.1.1)" (EC 2.8.1.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.8.1.1 or 2.8.1.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CJD2 at UniProt or InterPro

Protein Sequence (473 amino acids)

>Atu1215 thiosulfate sulfurtransferase (Agrobacterium fabrum C58)
MSTDKSRFVVSADWVEKQLGTAGFRVVDASWYLPAHKRNGAEEYAAGHLPGAVFFDQDKI
ADHTTGLPHSLPSPEFFAQEAGELGLSENDTIVVYDGPGFFSAPRVWWMLRVMGVRKAYV
LDGGLDGWKREGRPLETGTPEIEPATFTPDFNDKRVTSLSTMRGIVDSGEKQIADARGAG
RFTGDEAEPRAGMRSGHMPGARSLPAMAFSDNGHFKDLTAIRKMVTDAGIDLSKPVVTSC
GSGVTAAVVTLALESLGHHDNSLYDGSWSEWGGLEDTPVVTGAADPLPVISHGPLKAHVT
QLEMTAPPKVSLPIPVNLQTALMRVNNIPLHFYRYLYWRVGKRWHWQKRMRMSDAELSAI
LRDPKNSVTVLYMNGAPAGFFELNKASDEVTELSYFGLLEEAIGAGVGKWFLLQALYAAW
QDNPQRVTVTTNTLDHPRALQLYQMMGFSPVGTYEAWVEPLADTELLEISLRN