Protein Info for Atu1208 in Agrobacterium fabrum C58

Annotation: acyl-carrier-protein phosphodiesterase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 205 PF02525: Flavodoxin_2" amino acids 3 to 200 (198 residues), 167.6 bits, see alignment E=2.9e-53 PF03358: FMN_red" amino acids 3 to 173 (171 residues), 30.2 bits, see alignment E=3.2e-11

Best Hits

Swiss-Prot: 100% identical to AZOR_AGRFC: FMN-dependent NADH-azoreductase (azoR) from Agrobacterium fabrum (strain C58 / ATCC 33970)

KEGG orthology group: K01118, FMN-dependent NADH-azoreductase [EC: 1.7.-.-] (inferred from 100% identity to atu:Atu1208)

MetaCyc: 40% identical to FMN dependent NADH:quinone oxidoreductase (Escherichia coli K-12 substr. MG1655)
RXN0-5375 [EC: 1.7.1.17]; 1.6.5.- [EC: 1.7.1.17]

Predicted SEED Role

"FMN-dependent NADH-azoreductase"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.7.-.- or 1.7.1.17

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8UG34 at UniProt or InterPro

Protein Sequence (205 amino acids)

>Atu1208 acyl-carrier-protein phosphodiesterase (Agrobacterium fabrum C58)
MSNILLITSSPRGDESVSNKFAGELAGKLKAKSASNTLVHRDLAADPIPHLDTVKTAAIR
KPADQRTAEESVAADYSDKLVTELLAADTVVIGTGLINFNIYSGLKSWIDNVARAGQTFK
YTETGPVGLATGKKVYIVLAAAGVYSEGPAVSMNHAVPYLKTVLGFMGMTDVEVIYVEGL
AFGPEAVEKAVAAAEAKVEELAQAA