Protein Info for Atu1201 in Agrobacterium fabrum C58

Annotation: ABC transporter, nucleotide binding/ATPase protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 337 PF00005: ABC_tran" amino acids 45 to 196 (152 residues), 106.3 bits, see alignment E=2e-34 TIGR01727: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain" amino acids 245 to 331 (87 residues), 77.1 bits, see alignment E=4.3e-26 PF08352: oligo_HPY" amino acids 247 to 312 (66 residues), 57.7 bits, see alignment E=1.2e-19

Best Hits

Swiss-Prot: 46% identical to OPPF_ECOLI: Oligopeptide transport ATP-binding protein OppF (oppF) from Escherichia coli (strain K12)

KEGG orthology group: K02032, peptide/nickel transport system ATP-binding protein (inferred from 100% identity to atu:Atu1201)

MetaCyc: 46% identical to murein tripeptide ABC transporter / oligopeptide ABC transporter ATP binding subunit OppF (Escherichia coli K-12 substr. MG1655)
3.6.3.23-RXN [EC: 7.4.2.6]; 7.4.2.6 [EC: 7.4.2.6]

Predicted SEED Role

"Oligopeptide transport ATP-binding protein OppF (TC 3.A.1.5.1)" in subsystem ABC transporter oligopeptide (TC 3.A.1.5.1) (TC 3.A.1.5.1)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CJD7 at UniProt or InterPro

Protein Sequence (337 amino acids)

>Atu1201 ABC transporter, nucleotide binding/ATPase protein (Agrobacterium fabrum C58)
MMFSKAMTQMPPSAENGSRPYVVAKNLCKYYPISGLGHRVVKSVDDVSLTIGEGEVLGLV
GESGCGKSTVAGLITRLTHATRGEVSIGDHDILHMQGEALRRVRRVVQLVFQDPYSALDP
RMRIGQSMEAPLAQHGIGTRAERTARVFRMLEEVGLDGSFYDRYPNQCSGGQLQRVVIGR
ALLLNPSFLVCDEPTSALDASMRTQILNLLMDMKRRHGLTVLMISHDLRVVRYLCDRIAV
MYLGRIVEIADREELFRAPKHPYTKALIASSMLDETGLYAPEMLLDGDLPSPLNPPGGCK
FHTRCKYATAICGEVEPVLEGVSGEHFARCHRWRELG