Protein Info for Atu1198 in Agrobacterium fabrum C58

Annotation: ABC transporter, membrane spanning protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 314 transmembrane" amino acids 9 to 29 (21 residues), see Phobius details amino acids 101 to 126 (26 residues), see Phobius details amino acids 148 to 167 (20 residues), see Phobius details amino acids 178 to 195 (18 residues), see Phobius details amino acids 234 to 260 (27 residues), see Phobius details amino acids 280 to 304 (25 residues), see Phobius details PF19300: BPD_transp_1_N" amino acids 4 to 89 (86 residues), 35.1 bits, see alignment E=1.4e-12 PF00528: BPD_transp_1" amino acids 118 to 309 (192 residues), 120.8 bits, see alignment E=5.9e-39

Best Hits

Swiss-Prot: 37% identical to NIKB_ECOLI: Nickel transport system permease protein NikB (nikB) from Escherichia coli (strain K12)

KEGG orthology group: K02033, peptide/nickel transport system permease protein (inferred from 100% identity to atu:Atu1198)

MetaCyc: 37% identical to nickel ABC transporter membrane subunit NikB (Escherichia coli K-12 substr. MG1655)
7.2.2.i [EC: 7.2.2.i]; 7.2.2.- [EC: 7.2.2.i]

Predicted SEED Role

"Nickel transport system permease protein NikB (TC 3.A.1.5.3)" in subsystem Transport of Nickel and Cobalt (TC 3.A.1.5.3)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.2.2.i

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CJE0 at UniProt or InterPro

Protein Sequence (314 amino acids)

>Atu1198 ABC transporter, membrane spanning protein (Agrobacterium fabrum C58)
MWIQIIQRFFILCLMLAIVSIIAFLLPYMTGGDPARTILFSRMHDTALDPHAVEALRVSL
GLDRPLYVQYFTWLWNALRGDLGFSFTSSQPVANELLRSLGVSVTLALTALAVAVAVALP
LGTLAAMRPGGRLDNFATLMIQTFVATPEYWFAPMSALVFALYLGWLPSAGWDSWRSLVL
PALTLTLRPLAYFTQVTRAAMAEVLRAPYITAARSRGLGMHGTVMRHGIRNGSLPVVTFF
ALWLAGLLGGSVVVEVIFAIPGMGRLLYDAVINRDIPMLQGGFICIVALSILVNTLADSF
YVLINPAMRGQHDH