Protein Info for Atu1116 in Agrobacterium fabrum C58

Annotation: two component response regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 202 PF00072: Response_reg" amino acids 5 to 115 (111 residues), 84.6 bits, see alignment E=8.3e-28 PF08281: Sigma70_r4_2" amino acids 134 to 175 (42 residues), 28 bits, see alignment 2.1e-10 PF00196: GerE" amino acids 140 to 194 (55 residues), 57.1 bits, see alignment E=1.7e-19

Best Hits

Swiss-Prot: 34% identical to FIXJ_BRADU: Transcriptional regulatory protein FixJ (fixJ) from Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)

KEGG orthology group: None (inferred from 100% identity to atu:Atu1116)

Predicted SEED Role

"Transcriptional regulatory protein fixJ"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CJG9 at UniProt or InterPro

Protein Sequence (202 amino acids)

>Atu1116 two component response regulator (Agrobacterium fabrum C58)
MTLPVYLVDDDDAVRKALILLLSTVGIKAKGFADPVVFLGQLPALEPGCLIFDIRMPAIT
GLKLQEKLAEEGVDWPVIVISGHGNIEACRRAFHNGAVDFLSKPVDEQDLIDAIQKAHRI
LASTLDAKALHAETRALLALLTAREREILERIALGFTSRQIADGLGLSPRTVDSHRAAIG
LKLGTTSQAEMTRLWLEAGADQ