Protein Info for Atu1113 in Agrobacterium fabrum C58

Annotation: dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01408: GFO_IDH_MocA
  • amino acids 5 to 113 (109 residues), 64.2 bits, E=9.6e-22

Best Hits

Swiss-Prot: 58% identical to ARAA_AZOBR: L-arabinose 1-dehydrogenase (NAD(P)(+)) (araA) from Azospirillum brasilense

KEGG orthology group: K00035, D-galactose 1-dehydrogenase [EC: 1.1.1.48] (inferred from 100% identity to atu:Atu1113)

MetaCyc: 77% identical to galactose dehydrogenase (Sinorhizobium meliloti)
Galactose 1-dehydrogenase. [EC: 1.1.1.48]

Predicted SEED Role

"D-galactose 1-dehydrogenase (EC 1.1.1.48)" (EC 1.1.1.48)

MetaCyc Pathways

• D-galactose degradation II (2/2 steps found)

KEGG Metabolic Maps

• Galactose metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.1.1.48

Use Curated BLAST to search for 1.1.1.48

Sequence Analysis Tools

See Q7CZY7 at UniProt or InterPro

Protein Sequence (308 amino acids)

>Atu1113 dehydrogenase (Agrobacterium fabrum C58)
MSATKLAIVGVGKIVRDQHLPAIAGNPDFELICTASRHGTVDGVSSYGTIEAMLEAEPAI
NAVSLCMPPQYRYEAAYAALNAGKHVFLEKPPGATLSEVQDLARLADSKGLSLFASWHSR
YAPAVEAAKAFLASTTIDSVHVIWKEDVRHWHPNQAWIWQAGGLGVFDPGINALSIITHI
LPRALFLTKATLEFPENRDAPIAADLHFSDVEKTPVHAEFDWRQTGKQSWDIVAETAAGR
MVLSEGGAKLSINGEEKLSQPEREYPALYERFAEIIKAGRSDVDLAPLTHVADAFLLGRH
KFVDSFYD