Protein Info for Atu1112 in Agrobacterium fabrum C58

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 342 PF01590: GAF" amino acids 32 to 157 (126 residues), 42.9 bits, see alignment E=1.1e-14 PF13185: GAF_2" amino acids 32 to 159 (128 residues), 29.5 bits, see alignment E=1.2e-10 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 177 to 338 (162 residues), 144.3 bits, see alignment E=1.4e-46 PF00990: GGDEF" amino acids 179 to 336 (158 residues), 146.8 bits, see alignment E=7.3e-47

Best Hits

KEGG orthology group: None (inferred from 100% identity to atu:Atu1112)

Predicted SEED Role

"diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)" in subsystem Bacterial hemoglobins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7CZY8 at UniProt or InterPro

Protein Sequence (342 amino acids)

>Atu1112 hypothetical protein (Agrobacterium fabrum C58)
MGQAISRPDREVERLVAVRSVVAFKNAETDELRAISQLAQGVFDVARAAVHILDEDWLHI
AEQAGLQFQECSRDIAICDRVVVTQNVLTVSDLSVHPEFGWLPYVKGSPELRSYAGAPIE
LEPGLVVGTFCLLDPNVREYSPAEIDNLRYFATLAGALLRLQKANFTMSLAARELRDAAM
TDPLTGFYNRKALDAIVDLELGAALCERETFGVLYLDLDGFKAINDTLGHAAGDKVLVEA
AARIRDVVRAEDTVVRMGGDEFAIFVPRPMSASVIGSLAERLLEAFRQPFHVEGEDVLAR
LSIGGAIAPQAGADRPTLLRSVDEALYQAKKSGRDRFVSRAL