Protein Info for Atu0998 in Agrobacterium fabrum C58

Annotation: undecaprenyl pyrophosphate phosphatase, possible bacitracin resistance protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 278 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details transmembrane" amino acids 44 to 66 (23 residues), see Phobius details amino acids 89 to 108 (20 residues), see Phobius details amino acids 119 to 137 (19 residues), see Phobius details amino acids 150 to 169 (20 residues), see Phobius details amino acids 189 to 210 (22 residues), see Phobius details amino acids 221 to 243 (23 residues), see Phobius details amino acids 255 to 276 (22 residues), see Phobius details TIGR00753: undecaprenyl-diphosphatase UppP" amino acids 10 to 262 (253 residues), 258.4 bits, see alignment E=4e-81 PF02673: BacA" amino acids 10 to 264 (255 residues), 279.6 bits, see alignment E=1.5e-87

Best Hits

Swiss-Prot: 100% identical to UPPP2_AGRFC: Undecaprenyl-diphosphatase 2 (uppP2) from Agrobacterium fabrum (strain C58 / ATCC 33970)

KEGG orthology group: K06153, undecaprenyl-diphosphatase [EC: 3.6.1.27] (inferred from 100% identity to atu:Atu0998)

Predicted SEED Role

"Undecaprenyl-diphosphatase (EC 3.6.1.27)" (EC 3.6.1.27)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.1.27

Use Curated BLAST to search for 3.6.1.27

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P58741 at UniProt or InterPro

Protein Sequence (278 amino acids)

>Atu0998 undecaprenyl pyrophosphate phosphatase, possible bacitracin resistance protein (Agrobacterium fabrum C58)
MSMGWMEAGFLGLLQGLTEFLPVSSSAHLRIAGEFLPSGADPGAAFTAITQIGTEMAVLV
YFWSDIMRIAAAWLRQNLRLGEYNKADARLGWLIIVGSVPIVFLGLFFKDAIEHSLRNLY
ITAVMLIVFGIVLGLADRIGEKRYKLNQLIWRDGILFGFAQAMALIPGVSRSGGTISAGL
LLGYTREAAARYSFLLAVPAVFGSGFYQLFKSIGEDNPVGWGQTGLATLIAFIVGYAVIV
VFLKLVSTKSYMPFVWYRVVIGFILLALLGTGVISAGG