Protein Info for Atu0984 in Agrobacterium fabrum C58

Annotation: aminopeptidase N

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 882 TIGR02414: aminopeptidase N" amino acids 13 to 879 (867 residues), 1174.9 bits, see alignment E=0 PF17900: Peptidase_M1_N" amino acids 25 to 193 (169 residues), 48.1 bits, see alignment E=3e-16 PF01433: Peptidase_M1" amino acids 232 to 443 (212 residues), 189.5 bits, see alignment E=1.3e-59 PF11940: DUF3458" amino acids 451 to 553 (103 residues), 91.8 bits, see alignment E=5.9e-30 PF17432: DUF3458_C" amino acids 558 to 881 (324 residues), 336 bits, see alignment E=5.3e-104

Best Hits

KEGG orthology group: K01256, aminopeptidase N [EC: 3.4.11.2] (inferred from 100% identity to atu:Atu0984)

Predicted SEED Role

"Membrane alanine aminopeptidase N (EC 3.4.11.2)" (EC 3.4.11.2)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.11.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CJM4 at UniProt or InterPro

Protein Sequence (882 amino acids)

>Atu0984 aminopeptidase N (Agrobacterium fabrum C58)
MRTDTGQIVHLADYRPTDFVLERVDLTFELDPKNTKVEARLIFHRREGAERDAPLVLDGD
ELTLSSLLLDQVELPAGRYEATPDSLTIRDLPAESPFEICVTNYINPQVNTQLMGLYRTN
GVYCTQCEAEGFRRITYFPDRPDVLAPYTVTIIAAKEGNPLLLSNGNFLGGGNYDEGRHF
AAWFDPHPKPSYLFALVAGDLGVVEDTFTTMSGRDVALKIYVEHGKEPRAAYAMDALKRS
MKWDEERFGREYDLDIFMIVAVSDFNMGAMENKGLNVFNDKFVLADPETASDADYANIER
IIAHEYFHNWTGNRITCRDWFQLCLKEGLTVYRDQEFSADMRSRPVKRIADVRHLKSEQF
PEDSGPLAHPPRPDTYREINNFYTTTVYEKGAEVTRMIATILGADDFKKGMDLYFERHDG
EAATVEDFVKSFADASGRDLSQFSLWYTEAGTPLVSVSCAYDAGNAAFKLTLEQTVAPTP
GQPVKQPRHIPLSLALILDNGQIAEPQAVEGGEYRDGVLHLTERNQTFSFSGISSRPVLS
INRSFSAPINLDFEQNADDLVQIARHETDMFARFQALTDLALPALIAATRAVQNGEEIRT
DAALSATLIEIIGNDALEPAFRAQALALPSETDIARELGGNTDPDAIHKARNATIAAIAT
AGVETLRRLADGVANGEAYSPDADSAGRRSLRNGALSFLAFAEGTPERAAKAYADATNMT
DLAHALSVLTQRFPDSAETKEALAAFETRFADNALVLDKWFSLQAAIPGDGALDRIKTLM
KSKHFIATNPNRVRSLVGTLAFANPTGFHRADGAAYRFLAEQIIAIDKRNPQLAARILTS
MRSWRSLEASRAEHAKAALSTIAEAKGLSTDVSDIVGRILKG