Protein Info for Atu0974 in Agrobacterium fabrum C58

Annotation: cytochrome-c biosynthesis heme-carrier protein cycJ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 165 transmembrane" amino acids 9 to 36 (28 residues), see Phobius details PF03100: CcmE" amino acids 33 to 130 (98 residues), 114.8 bits, see alignment E=1e-37

Best Hits

Swiss-Prot: 100% identical to CCME_AGRFC: Cytochrome c-type biogenesis protein CcmE (ccmE) from Agrobacterium fabrum (strain C58 / ATCC 33970)

KEGG orthology group: K02197, cytochrome c-type biogenesis protein CcmE (inferred from 100% identity to atu:Atu0974)

Predicted SEED Role

"Cytochrome c-type biogenesis protein CcmE, heme chaperone" in subsystem Biogenesis of c-type cytochromes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8UGR1 at UniProt or InterPro

Protein Sequence (165 amino acids)

>Atu0974 cytochrome-c biosynthesis heme-carrier protein cycJ (Agrobacterium fabrum C58)
MTRKQKRLAIIGGGMSFIVAAVLLVMFAFGQSIAYFYMPADLEKTPVNPGTRIRLGGLVA
EGSIKRGEGRTVSFTVTDGEAKVPVSYTGILPDLFREGQGVVTEGMFDAATHGFVADSVL
AKHDENYMPKEVADRLKDKGLWQQGAEGAAPAASAASGDKTGATK