Protein Info for Atu0928 in Agrobacterium fabrum C58

Annotation: transcriptional regulator, LysR family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 301 TIGR03298: transcriptional regulator, ArgP family" amino acids 2 to 296 (295 residues), 389.8 bits, see alignment E=3.4e-121 PF00126: HTH_1" amino acids 7 to 62 (56 residues), 63.1 bits, see alignment E=1.8e-21 PF03466: LysR_substrate" amino acids 92 to 272 (181 residues), 51.7 bits, see alignment E=7.9e-18

Best Hits

Swiss-Prot: 45% identical to Y1985_MYCTU: Uncharacterized HTH-type transcriptional regulator Rv1985c (Rv1985c) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

KEGG orthology group: K05596, LysR family transcriptional regulator, chromosome initiation inhibitor (inferred from 100% identity to atu:Atu0928)

Predicted SEED Role

"Transcriptional regulator, LysR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CJQ0 at UniProt or InterPro

Protein Sequence (301 amino acids)

>Atu0928 transcriptional regulator, LysR family (Agrobacterium fabrum C58)
MLDYPSMRAVALVARTGSFEKAAQVLCVTPSAVSQRIKQLEERLGVVLIVRGNPCVATEK
GEWLCRHMDHVGMLESELFRQLPALTEAGDAQERVTLNIATNADSLGTWFLDAVSKFTGG
SDYLVNIAVDDQDHTVEWLRGGRVLAAVTAHDKPVQGCRVTPLGVLRYHATASPDFMARH
FADGVTPAALARAPGLTFNQKDRLQASWIRTALGEDVSYPTHWLPSTDGFVKASLAGMGW
GLNPVQLVAEHLAAGRLVELMPGTPLDIPLYWQVNRLAAERLAGLTANMVGTARVVLMPV
G