Protein Info for Atu0909 in Agrobacterium fabrum C58

Annotation: Na+/H+ antiporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 789 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details transmembrane" amino acids 34 to 53 (20 residues), see Phobius details amino acids 58 to 80 (23 residues), see Phobius details amino acids 84 to 103 (20 residues), see Phobius details amino acids 115 to 131 (17 residues), see Phobius details amino acids 137 to 155 (19 residues), see Phobius details amino acids 167 to 190 (24 residues), see Phobius details amino acids 211 to 234 (24 residues), see Phobius details amino acids 247 to 264 (18 residues), see Phobius details amino acids 276 to 296 (21 residues), see Phobius details amino acids 303 to 323 (21 residues), see Phobius details amino acids 330 to 352 (23 residues), see Phobius details amino acids 373 to 392 (20 residues), see Phobius details amino acids 412 to 433 (22 residues), see Phobius details amino acids 453 to 480 (28 residues), see Phobius details amino acids 500 to 522 (23 residues), see Phobius details amino acids 571 to 590 (20 residues), see Phobius details amino acids 606 to 624 (19 residues), see Phobius details amino acids 631 to 650 (20 residues), see Phobius details amino acids 656 to 678 (23 residues), see Phobius details amino acids 690 to 710 (21 residues), see Phobius details amino acids 752 to 770 (19 residues), see Phobius details PF00662: Proton_antipo_N" amino acids 70 to 115 (46 residues), 49.2 bits, see alignment 7.9e-17 PF00361: Proton_antipo_M" amino acids 132 to 415 (284 residues), 221.4 bits, see alignment E=3.1e-69 PF13244: MbhD" amino acids 613 to 677 (65 residues), 59.9 bits, see alignment E=4.5e-20 PF20501: MbhE" amino acids 690 to 773 (84 residues), 69 bits, see alignment E=6.1e-23

Best Hits

KEGG orthology group: K05565, multicomponent Na+:H+ antiporter subunit A (inferred from 100% identity to atu:Atu0909)

Predicted SEED Role

"Na(+) H(+) antiporter subunit A" in subsystem Sodium Hydrogen Antiporter

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CJR3 at UniProt or InterPro

Protein Sequence (789 amino acids)

>Atu0909 Na+/H+ antiporter (Agrobacterium fabrum C58)
MTSDVTALTFLSLFLPFLAALAAPALVKRFGHNAAWIIAIAPAFAFVHFALMLPQIAAGG
VVTGGYAWVPSFNLSFSWFIDGLSLTFALLITGIGVLIVLYAGGYMKGHPQQGRFLSFLL
LFMGAMLGVVVSDSVLMLFVFWELTSITSFLLIGFDHERAASRRAALQALVVTGGGGLLL
LAGLIFIWDISGLTQLSMLVRGGDILRDSPFYLAALLLVLGGAFTKSAQFPFHFWLPNAM
EAPTPVSAYLHSATMVKAGVYLLMRLNPVLGDTAAWQILLPFFGGLTMLTGALLAVRQTD
LKLMLAYTTVSSLGLLVMLTGFGSDHAIEAAVLYLVAHSLFKGALFMVAGIIDHETGTRD
VTKLAGLRKAMPITFAAALAAAISMAGLPPFFGFLAKEEIYYALAHGNPRAVLFTGIAIL
GNGLMFAVAFAVGLKPFLGKPVKTPKNAHEGPLLLWLGPALLALKGFTIALFAGIAHFYI
STPMASAIAGEPRPVEISLIPHIGVPLGLSLLTIALGITLYTQLSRVRSLMDRSFKALGA
GPDRGFDVFIETLVRMSFHVTRLIQPGRLEFYVTATFAVIAAVLLVPLFLYDELPSIPAW
PHDMPIHELTFIVIAVAGLLAVLTASSRLTAIIALGIQGFAVAVIFLLFGAPDLSFTQFM
VETLSVVILTLVMTRLRLSPSDHRGLGQKLLDSTIAIACGTGFALFLMRATQASFDNRLT
DFYNTYSKVIAHGANVVNVIIVDFRGTDTLGEIAVVMITGLAILALIRIRPAAVLKGPAK
TVKKKGART