Protein Info for Atu0908 in Agrobacterium fabrum C58

Annotation: transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00357: methionine-R-sulfoxide reductase
  • amino acids 11 to 134 (124 residues), 181.1 bits, E=4.6e-58
• PF01641: SelR
  • amino acids 20 to 134 (115 residues), 177.2 bits, E=4.7e-57

Best Hits

Swiss-Prot: 100% identical to MSRB_AGRFC: Peptide methionine sulfoxide reductase MsrB (msrB) from Agrobacterium fabrum (strain C58 / ATCC 33970)

KEGG orthology group: K07305, peptide-methionine (R)-S-oxide reductase [EC: 1.8.4.12] (inferred from 100% identity to atu:Atu0908)

MetaCyc: 51% identical to methionine sulfoxide reductase B (Escherichia coli K-12 substr. MG1655)
L-methionine (R)-S-oxide reductase. [EC: 1.8.4.14]; Peptide-methionine (R)-S-oxide reductase. [EC: 1.8.4.14, 1.8.4.12]

Predicted SEED Role

"Peptide methionine sulfoxide reductase MsrB (EC 1.8.4.12)" (EC 1.8.4.12)

KEGG Metabolic Maps

• Methionine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.8.4.12 or 1.8.4.14

Sequence Analysis Tools

See Q8UGX7 at UniProt or InterPro

Protein Sequence (135 amino acids)

>Atu0908 transcriptional regulator (Agrobacterium fabrum C58)
MSDLTSPKVNKSDADWREQLTPEQYHILREHGTERPFTGPYWNSTEKGLYRCAACDEPLF
LSDTKFDAGCGWPSYFEPVKPGAVTEHRDSTHGMVRTEIRCANCGGHLGHVFPDGPPPTG
LRYCINGHSMVFEPV