Protein Info for Atu0891 in Agrobacterium fabrum C58

Annotation: cation efflux system protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 335 transmembrane" amino acids 29 to 50 (22 residues), see Phobius details amino acids 62 to 79 (18 residues), see Phobius details amino acids 99 to 118 (20 residues), see Phobius details amino acids 131 to 151 (21 residues), see Phobius details amino acids 202 to 222 (21 residues), see Phobius details amino acids 228 to 248 (21 residues), see Phobius details TIGR01297: cation diffusion facilitator family transporter" amino acids 25 to 333 (309 residues), 226.8 bits, see alignment E=1.6e-71 PF01545: Cation_efflux" amino acids 30 to 259 (230 residues), 122.8 bits, see alignment E=8.2e-40

Best Hits

KEGG orthology group: None (inferred from 100% identity to atu:Atu0891)

Predicted SEED Role

"Cobalt-zinc-cadmium resistance protein CzcD" in subsystem Cobalt-zinc-cadmium resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7D0F5 at UniProt or InterPro

Protein Sequence (335 amino acids)

>Atu0891 cation efflux system protein (Agrobacterium fabrum C58)
MTTTSEPFAAAEHHHIYLGQNHERNERRVWMVIALTTVMMVAEIVAGHWFGSMALTADGW
HMSTHAGAMLISALAYLYARREARNPRFSFGTGKFGDLAGFASAVVLAVVALLIAVESGL
RLVSPVQIDFNQAILVAVIGLVVNLVSAVLLKDDHHHDRGHGHGHGHASHAHHGHGSHAH
HDHGSHAQHGAKGGRDNNLRAAYLHVLADALTSVLAIVALLLGKWNGWNFLDPLMGIVGG
LVIARWSWGLIRSTATTLVDAVPLTDDLPQEIRDTVETEEDRITDLHVWQVGPGHHAAIV
AIHSQAPKAPAFYKQKLAAIHELSHVTVEVSPASA