Protein Info for Atu0695 in Agrobacterium fabrum C58

Annotation: 3-deoxy-D-manno-octulosonic acid transferase-like protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 440 transmembrane" amino acids 12 to 21 (10 residues), see Phobius details amino acids 59 to 76 (18 residues), see Phobius details PF04413: Glycos_transf_N" amino acids 43 to 214 (172 residues), 190 bits, see alignment E=1.4e-60

Best Hits

KEGG orthology group: K02527, 3-deoxy-D-manno-octulosonic-acid transferase [EC: 2.-.-.-] (inferred from 100% identity to atu:Atu0695)

MetaCyc: 56% identical to lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase (Brucella abortus 2308)
RXN2B4Q-55 [EC: 2.4.99.13]; RXN2B4Q-54 [EC: 2.4.99.13, 2.4.99.12]

Predicted SEED Role

No annotation

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.-.-.-

Use Curated BLAST to search for 2.-.-.- or 2.4.99.12 or 2.4.99.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CK11 at UniProt or InterPro

Protein Sequence (440 amino acids)

>Atu0695 3-deoxy-D-manno-octulosonic acid transferase-like protein (Agrobacterium fabrum C58)
MSSRLARFALSGYRIAGIAAYPFARPYLSYRAAKGKEDKRRRLERFGYASAERPRGPLVW
FHAASVGETLALIPLIREIRKRDIFVLLTTGTVTSAELTRTRLGDDVIHQYVPLDIKIAV
NRFLTYWAPDAAITAESEIWPVTMMELERRHIPQIRVNARLSDRSFDRWKARHDIAESLF
SKLALVVAQSDLDAERFRDLGSWPVVISGNLKGDTDPPPCDEALLESYRKQVGNRKTWAA
ISTFDGEEKAAATVHAAIKSRNGQLTIIVPRHPERGDDVEAMLKGMNLSVARRSRNDVIT
PGTDIFLGDSIGEMGLYLRLTELAFVGRSLTAEGGQNPLEPAMLGCAVLSGAHVQNFREA
YQKLIRAGGGRIIRDVEMLAKAVHYLLVNDNERYKMIDAGNRVIQDMRGALSSTVKALEP
YINPLTVSAKLQPRSAIGSW