Protein Info for Atu0612 in Agrobacterium fabrum C58

Annotation: ABC transporter, membrane spanning protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 270 transmembrane" amino acids 9 to 30 (22 residues), see Phobius details amino acids 60 to 84 (25 residues), see Phobius details amino acids 96 to 123 (28 residues), see Phobius details amino acids 129 to 149 (21 residues), see Phobius details amino acids 174 to 196 (23 residues), see Phobius details amino acids 231 to 252 (22 residues), see Phobius details PF00528: BPD_transp_1" amino acids 74 to 244 (171 residues), 60.3 bits, see alignment E=1.1e-20

Best Hits

Swiss-Prot: 55% identical to POTI_ECOLI: Putrescine transport system permease protein PotI (potI) from Escherichia coli (strain K12)

KEGG orthology group: K11074, putrescine transport system permease protein (inferred from 100% identity to atu:Atu0612)

MetaCyc: 55% identical to putrescine ABC transporter membrane subunit PotI (Escherichia coli K-12 substr. MG1655)
ABC-25-RXN [EC: 7.6.2.11, 7.6.2.16]

Predicted SEED Role

"Putrescine transport system permease protein PotI (TC 3.A.1.11.2)" in subsystem Polyamine Metabolism (TC 3.A.1.11.2)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.6.2.11 or 7.6.2.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CK49 at UniProt or InterPro

Protein Sequence (270 amino acids)

>Atu0612 ABC transporter, membrane spanning protein (Agrobacterium fabrum C58)
MKRGKFDITVLTLGFAFLYIPIIILIIYSFNASKLVTVWGGFSLQWYKSMWSNQGLMDAA
WVTLRVGILSATIGTILGTLAALSLTRFARFPGRVLFSGMIYAPLVMPEVITGLSLLLLF
VAVGVDRGFWTVVIAHTTFTMCYVAIVVQSRLLTFDRSLEEAALDLGCPPVKTFFRITLP
LIFPAVIAGWMLAFTLSLDDLVIASFATGPGATTLPIKIYSQVRLGVTPEINAICTILIG
LVTIGVIAASVASKRTELQRMRDEHAAARN