Protein Info for Atu0594 in Agrobacterium fabrum C58

Annotation: alpha-glucosidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 551 PF00128: Alpha-amylase" amino acids 38 to 389 (352 residues), 302.4 bits, see alignment E=8.7e-94 PF11941: DUF3459" amino acids 461 to 547 (87 residues), 32.8 bits, see alignment E=1.1e-11 PF16657: Malt_amylase_C" amino acids 482 to 546 (65 residues), 30.5 bits, see alignment E=4.8e-11

Best Hits

Swiss-Prot: 76% identical to AGLA_RHIME: Probable alpha-glucosidase (aglA) from Rhizobium meliloti (strain 1021)

KEGG orthology group: K01187, alpha-glucosidase [EC: 3.2.1.20] (inferred from 100% identity to atu:Atu0594)

Predicted SEED Role

"Alpha-glucosidase AglA"

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.20

Use Curated BLAST to search for 3.2.1.20

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7D153 at UniProt or InterPro

Protein Sequence (551 amino acids)

>Atu0594 alpha-glucosidase (Agrobacterium fabrum C58)
MTASVTSALTPNKDWWRGAVIYQIYPRSYQDSNGDGIGDLKGITDRLHHIAGLGADAIWI
SPFFTSPMKDFGYDVSNYVDVDPMFGTLADFDGLIAEAHRLGIRVMIDLVLSHTSDQHPW
FVESRASRNNPKSDWYVWSEAKPDGTPPNNWLSIFGGSGWQWDPTRMQYYMHNFLTSQPD
LNLHNPEVQEELLNITRFWLKRGVDGFRLDTINFYFHDLELRDNPALAPERRNASTAPAV
NPYNFQEHLYDKNRPENIAFLKRFRAVLDEFPDIAAVGEVGDSQRGLEIVGEYTSGDDKM
QMCYAFEFLAPDALTPQRVADVQADFARAAPEGWACWAFSNHDVVRHVSRWGEHVEDKDA
FAKLLSALLMTQRGSVCIYEGEELGLTEADIAFEDLQDPYGIQFWPEFKGRDGCRTPMVW
DAGHAQAGFSTSDKIWLPIPAEHKQRAVSAQQGNEASVLEHYRRFLAFRKQHPAFAKGGI
EFQPLEGDVLSYTRKLGNETILCLFNLSATPANATLPKGNWEVLEGHGFASGLEGTSVEL
PAWGAFFARYA