Protein Info for Atu0581 in Agrobacterium fabrum C58

Annotation: flagellar biosynthesis protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 695 transmembrane" amino acids 20 to 38 (19 residues), see Phobius details amino acids 44 to 62 (19 residues), see Phobius details amino acids 74 to 94 (21 residues), see Phobius details amino acids 114 to 137 (24 residues), see Phobius details amino acids 206 to 227 (22 residues), see Phobius details amino acids 247 to 265 (19 residues), see Phobius details amino acids 288 to 324 (37 residues), see Phobius details TIGR01398: flagellar biosynthesis protein FlhA" amino acids 17 to 694 (678 residues), 890 bits, see alignment E=5.1e-272 PF00771: FHIPEP" amino acids 28 to 685 (658 residues), 784.2 bits, see alignment E=5.9e-240

Best Hits

Swiss-Prot: 72% identical to FLHA_BRUME: Flagellar biosynthesis protein FlhA (flhA) from Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)

KEGG orthology group: K02400, flagellar biosynthesis protein FlhA (inferred from 100% identity to atu:Atu0581)

Predicted SEED Role

"Flagellar biosynthesis protein FlhA" in subsystem Flagellar motility or Flagellum

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7D165 at UniProt or InterPro

Protein Sequence (695 amino acids)

>Atu0581 flagellar biosynthesis protein (Agrobacterium fabrum C58)
MAQPPVISLPKVSPSMRDIGFALGIISILCVLFLPIPVMLVDIGLAFSIALSVLILMVAL
WIQRPLDFSSFPTVLLIATMIRLSLNIATTRVILSHGNEGPTAAGGVIAGFSSLVMSGDF
VIGLIVFLILITVNFIVITKGATRIAEVGARFTLDAIPGKQMSIDADLSAGIIDEKEAQR
RRRELEEESSFFGSMDGASKFVRGDAIAGLIITAINVFGGIIIGYFRHGMPIGEAADVFV
KLSVGDGIVSQIPALIVSLAAGLLVSRGGTAGSTDQAVINQLSGYPRALMVSAMLMGLLA
VIPGLPFVPFIFLGGIMAFGSWYIPRQAEAESALRRQEEENKVLQTTEAEKDSVKQVLKT
AEIELALGKQVSTRLLGAHQELAFRVGKMRKKFATQYGFVVPEIKVSDDIMIPEKAYQIR
VHGTTIASSNLRVGDVLVVTGAGRKPSIPGDEIREPAFGMPAVSILETFTEDLKREGFHP
IDNVSVVLTHLSEVIRNNLPQLLSYKDVKILIDRLDPEYKKLADEICSSHMSYSGLQAVL
KLLLAERVSIRNLHLILEAVAELAPHVRKTEQIVEHVRVRMSQQLCGDLADNGVLRVLRL
GNKWDMVFHQALKRDQKGEIVEFDIDPRHLEEFSEQASKVIREFMDRGLPFVLVTSPETR
SYVRMIIERLFATLPVLSHVELAKGLEIKILGAIS