Protein Info for Atu0533 in Agrobacterium fabrum C58

Annotation: putative inhibitor of septum formation

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 207 TIGR00172: septum formation protein Maf" amino acids 5 to 193 (189 residues), 163.4 bits, see alignment E=2.1e-52 PF02545: Maf" amino acids 7 to 194 (188 residues), 197.9 bits, see alignment E=6.6e-63

Best Hits

Swiss-Prot: 100% identical to NTPPA_AGRFC: dTTP/UTP pyrophosphatase (maf1) from Agrobacterium fabrum (strain C58 / ATCC 33970)

KEGG orthology group: K06287, septum formation protein (inferred from 100% identity to atu:Atu0533)

Predicted SEED Role

"Septum formation protein Maf" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8UHX5 at UniProt or InterPro

Protein Sequence (207 amino acids)

>Atu0533 putative inhibitor of septum formation (Agrobacterium fabrum C58)
MTNSKQKLVLASGSPRRLELLHQIGIEPARLMPMDIDETPVKLEHPRTLCRRLSQQKAEA
AQAALKSEQAWKDAYVLGSDTVVAVGRRIVGKAEYTEEASAALHLLSGRSHWVYTGICLV
TPDGKIRQKVAETKVRFKRLSTREIDAYIASGQWRGKAGAYGIQGIAGAFVQKLTGSYTN
VVGLPLYETMSLLSGEGFEVTSGWLEG