Protein Info for Atu0489 in Agrobacterium fabrum C58

Annotation: methyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 278 PF13489: Methyltransf_23" amino acids 94 to 222 (129 residues), 38.7 bits, see alignment E=2.1e-13 PF13847: Methyltransf_31" amino acids 112 to 218 (107 residues), 37.7 bits, see alignment E=4.2e-13 PF13649: Methyltransf_25" amino acids 113 to 210 (98 residues), 36 bits, see alignment E=2.3e-12 PF08241: Methyltransf_11" amino acids 114 to 214 (101 residues), 34.2 bits, see alignment E=8.5e-12 PF08242: Methyltransf_12" amino acids 114 to 212 (99 residues), 38.5 bits, see alignment E=4.1e-13

Best Hits

KEGG orthology group: None (inferred from 100% identity to atu:Atu0489)

Predicted SEED Role

"SAM-dependent methyltransferases"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7D1D2 at UniProt or InterPro

Protein Sequence (278 amino acids)

>Atu0489 methyltransferase (Agrobacterium fabrum C58)
MEQALELAPRWTAGWFRFGEYHEKAGETAKAVAAYEKVAELDAEGLFAAELKLAVLGAAE
TPEQPPSRYVEGLFDDYADRFETSLVEKLDYSVPQKLAELIGKAATGDAFDTIVDIGCGT
GLLGIEIRSLAKRLEGFDISQNMLAKADEKSLYDHLGQADLSLDAEASGLFTPVLTQHRA
DLVAAADVMMYLGSLETVMPLVSALLKPSGFFAFSVEDAGDEQGFVLRESLRYAHSKSYV
IDLLERSGFSPMEIRKTTIRKDAGKPLSGILFLARAKA