Protein Info for Atu0476 in Agrobacterium fabrum C58

Annotation: aquaporin

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 241 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details transmembrane" amino acids 36 to 57 (22 residues), see Phobius details amino acids 81 to 103 (23 residues), see Phobius details amino acids 127 to 148 (22 residues), see Phobius details amino acids 157 to 178 (22 residues), see Phobius details amino acids 203 to 224 (22 residues), see Phobius details PF00230: MIP" amino acids 2 to 220 (219 residues), 169.1 bits, see alignment E=6.4e-54 TIGR00861: MIP family channel proteins" amino acids 7 to 221 (215 residues), 188.2 bits, see alignment E=9e-60

Best Hits

Swiss-Prot: 100% identical to AQPZ1_AGRFC: Aquaporin Z 1 (aqpZ1) from Agrobacterium fabrum (strain C58 / ATCC 33970)

KEGG orthology group: K06188, aquaporin Z (inferred from 100% identity to atu:Atu0476)

MetaCyc: 68% identical to water channel AqpZ (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-145

Predicted SEED Role

"Aquaporin Z"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8UI24 at UniProt or InterPro

Protein Sequence (241 amino acids)

>Atu0476 aquaporin (Agrobacterium fabrum C58)
MSRKFISEFLGTFWLVFGGCGSAVFAAAFPELGIGFLGVAFAFGLTVLTMAYAVGGISGG
HFNPAVSVGLTVAGKFPAANLVPYIVAQVLGAVVAAAALYVILTGKAGAEIGGFAANGYG
EHSPGGYSLLSALLIEIILTAFFLVVILGSTHGRVPVGFAPVAIGLALTLIHLISIPVTN
TSVNPARSTGQALFVGGWALQQLWLFWLAPILGGAIGAVVWKIFGEEEKAGHAGSVQPAK
T