Protein Info for Atu0384 in Agrobacterium fabrum C58

Annotation: preprotein translocase 60 kD membrane subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 599 transmembrane" amino acids 6 to 25 (20 residues), see Phobius details amino acids 371 to 397 (27 residues), see Phobius details amino acids 442 to 466 (25 residues), see Phobius details amino acids 501 to 522 (22 residues), see Phobius details amino acids 536 to 561 (26 residues), see Phobius details TIGR03593: membrane protein insertase, YidC/Oxa1 family, N-terminal domain" amino acids 4 to 376 (373 residues), 333.3 bits, see alignment E=2.6e-103 PF14849: YidC_periplas" amino acids 87 to 366 (280 residues), 254.2 bits, see alignment E=2.4e-79 TIGR03592: membrane protein insertase, YidC/Oxa1 family" amino acids 377 to 575 (199 residues), 229.7 bits, see alignment E=3e-72 PF02096: 60KD_IMP" amino acids 378 to 575 (198 residues), 211.2 bits, see alignment E=9.1e-67

Best Hits

Swiss-Prot: 100% identical to YIDC_AGRFC: Membrane protein insertase YidC (yidC) from Agrobacterium fabrum (strain C58 / ATCC 33970)

KEGG orthology group: K03217, preprotein translocase subunit YidC (inferred from 100% identity to atu:Atu0384)

Predicted SEED Role

"Inner membrane protein translocase component YidC, long form"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8UIB3 at UniProt or InterPro

Protein Sequence (599 amino acids)

>Atu0384 preprotein translocase 60 kD membrane subunit (Agrobacterium fabrum C58)
MEKNRNYFIAIALSVVIVLAWQFLYMNPRIEQQRRAEEARQAQQQTTQQQPAPGAAPGAT
VEGAPPASSTQAAATATREEAIARTQRVAIDTNAIAGSINLTGARFDDIRLKGYHETVDD
SSPIITLFSPADTKDGYFTELGYVAAQEVGGVPGPTTVWTLASGDKLTETTPVTLTYTNS
KGVVFSRTVSIDEHYMLSIADKVENPGQAAISFATYGRVTRNNKPVIPPVFVIHEGFLGV
SGKDGSLTEKKYKDVEEEPVTVAKATGGWLGITDKYWAAAIVPPQTTPFETRYSHITGNQ
PSYQADFKSDSMTVEAGQSIELKSLVFAGAKEVPLVDRYETEYSVPKFDLLIDWGWFYFI
TKPMFKMMDFFFRYFGNFGVAILLTTIVVKALFFPLASKQYASMANMKRMQPKMEELKAK
HGDDRMAMQQAMMQLYKEEKINPVAGCWPMLLQIPVFFALYKVIYVTIEMRHAPFFGWIH
DLSAPDPTSLFNLFGLLPYDVPHFLMIGVWPLVMGITMFLQMRMNPTPPDPTQAMIFTWM
PLIFTFMLASFPAGLVIYWAWNNTLSISQQALIMKRHGAKIELFDNIKGLFKRKPVQSK