Protein Info for Atu0341 in Agrobacterium fabrum C58

Annotation: rRNA methylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 286 PF22435: MRM3-like_sub_bind" amino acids 24 to 114 (91 residues), 87.8 bits, see alignment E=7.9e-29 PF08032: SpoU_sub_bind" amino acids 47 to 118 (72 residues), 31.1 bits, see alignment E=3.7e-11 PF00588: SpoU_methylase" amino acids 133 to 273 (141 residues), 128.5 bits, see alignment E=3.2e-41

Best Hits

KEGG orthology group: K03437, RNA methyltransferase, TrmH family (inferred from 100% identity to atu:Atu0341)

Predicted SEED Role

"macromolecule metabolism; macromolecule synthesis, modification; rna synthesis, modification , dna transcription"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7D1N4 at UniProt or InterPro

Protein Sequence (286 amino acids)

>Atu0341 rRNA methylase (Agrobacterium fabrum C58)
MTKDMRENITRRVGQVKEVTSLANPIIKDIKALTQKKGREETGTFMAEGLKLVIDALELG
WTIKTLVYAKAAKGKPLVEQAAVKTVASGGLVLEVSEKVIASITRRDNPQMVVGIFEQKW
KPLKDIRPEKGETYIALDRVRDPGNLGTIIRTADAAGASGVILVGDCTDPFSLETVRATM
GSVFATPVARASVEEFLSWKKSAHVSVVATHLAGSVDYRKIDYAGKPVVILMGNEQSGLP
PELAGKADQLARIPQQGRADSLNLAIATAVMLFEARRHLLELAPVT