Protein Info for Atu0217 in Agrobacterium fabrum C58

Annotation: components of type IV pilus

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 334 transmembrane" amino acids 6 to 25 (20 residues), see Phobius details amino acids 107 to 126 (20 residues), see Phobius details amino acids 132 to 152 (21 residues), see Phobius details amino acids 269 to 293 (25 residues), see Phobius details amino acids 308 to 326 (19 residues), see Phobius details PF00482: T2SSF" amino acids 167 to 291 (125 residues), 72.4 bits, see alignment E=1.7e-24

Best Hits

KEGG orthology group: K12510, tight adherence protein B (inferred from 100% identity to atu:Atu0217)

Predicted SEED Role

"Flp pilus assembly protein TadB" in subsystem Widespread colonization island

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CKJ7 at UniProt or InterPro

Protein Sequence (334 amino acids)

>Atu0217 components of type IV pilus (Agrobacterium fabrum C58)
MDPTIVLLAVLVAISAGALAYAFLFQQIEVEKKTTSRFKRVQAAETDHTNIKAARDRVQE
LSKRRKSMQDSLRDMEKKQNEKAKKAKNVSLRDKLVQAGLTISVRQFHLLSAGAAACAAF
ISLIYGLSLLTALPIAVVAALGLPRWVLAFLLKRRQKKFLEEFPNALDVMCRSIKSGLPL
NDAVRLIASDGQEPVKTEFQRVVDAQQVGIGIPQGIERMMLTMPLFEVSFFSIVINIQAQ
AGGNLSEALSNLSRVLRDRRKMRAKVNALSMEAKASAVIIGALPFIVMLLVHFTSPDYLS
ILFTDTRGHLILGASAIWMLIGIFIMRQMINFDI