Protein Info for Atu0198 in Agrobacterium fabrum C58

Annotation: ABC transporter, membrane spanning protein (proline/glycine/betaine)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 381 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details transmembrane" amino acids 38 to 59 (22 residues), see Phobius details amino acids 67 to 88 (22 residues), see Phobius details amino acids 102 to 120 (19 residues), see Phobius details amino acids 129 to 149 (21 residues), see Phobius details amino acids 175 to 195 (21 residues), see Phobius details amino acids 209 to 232 (24 residues), see Phobius details amino acids 241 to 271 (31 residues), see Phobius details amino acids 292 to 312 (21 residues), see Phobius details amino acids 318 to 338 (21 residues), see Phobius details amino acids 345 to 367 (23 residues), see Phobius details PF00528: BPD_transp_1" amino acids 187 to 366 (180 residues), 76.5 bits, see alignment E=1.1e-25

Best Hits

KEGG orthology group: K05846, osmoprotectant transport system permease protein (inferred from 100% identity to atu:Atu0198)

Predicted SEED Role

"L-proline glycine betaine ABC transport system permease protein ProW (TC 3.A.1.12.1)" in subsystem Choline and Betaine Uptake and Betaine Biosynthesis (TC 3.A.1.12.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CKK8 at UniProt or InterPro

Protein Sequence (381 amino acids)

>Atu0198 ABC transporter, membrane spanning protein (proline/glycine/betaine) (Agrobacterium fabrum C58)
MGVLISCLLLYALFASPFMTFRANRIVQGETRTIFEALPSAAATLLAAIILLAVFFAFFR
FPAWLKLAAALAGLAALAVFVGQAASFLTPDGNSFARVSPSSGFWFLFVGLALLATDCIA
RLEPKPAIRILLLLLAIAALSAILASGLWNDLSIIKEYTGRADIFWIEAVRHVELAIGSL
IAATVAGIPLGILCYKVERLRAGVLNSLNIVQTIPSIALFGLLIAPLGWIAATVPGAARI
GIAGIGMAPAFVALFLYSLLPVVSNTVVGLAGVSHAIREAARGLGMTPVQRLLRVEFPLA
MPVILTGIRIVLVQNIGLATIAALIGGGGFGVFVFQGIGQTAMDLVLLGTVPTVLLGFAA
AITLDALIDSNLFSAGGRQKP