Protein Info for Atu0196 in Agrobacterium fabrum C58

Annotation: ABC transporter, membrane spanning protein (proline/glycine/betaine)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 246 signal peptide" amino acids 1 to 38 (38 residues), see Phobius details transmembrane" amino acids 53 to 77 (25 residues), see Phobius details amino acids 95 to 114 (20 residues), see Phobius details amino acids 121 to 146 (26 residues), see Phobius details amino acids 167 to 191 (25 residues), see Phobius details amino acids 212 to 235 (24 residues), see Phobius details PF00528: BPD_transp_1" amino acids 88 to 235 (148 residues), 73.8 bits, see alignment E=7.6e-25

Best Hits

Swiss-Prot: 47% identical to YEHW_ECOLI: Glycine betaine uptake system permease protein YehW (yehW) from Escherichia coli (strain K12)

KEGG orthology group: K05846, osmoprotectant transport system permease protein (inferred from 100% identity to atu:Atu0196)

MetaCyc: 47% identical to glycine betaine ABC transporter membrane subunit YehW (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-283

Predicted SEED Role

"L-proline glycine betaine ABC transport system permease protein ProW (TC 3.A.1.12.1)" in subsystem Choline and Betaine Uptake and Betaine Biosynthesis (TC 3.A.1.12.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7D1Z7 at UniProt or InterPro

Protein Sequence (246 amino acids)

>Atu0196 ABC transporter, membrane spanning protein (proline/glycine/betaine) (Agrobacterium fabrum C58)
MKNAFSFLSLGLLVLALIIFLAAPQIFAPIFRPLVQANAPAIYTQANLFSLTLSHLTIVA
IATGLATLTAGALAVLVTRPFGADFLPLSRSIVNIGQTFPPVAVLALAVPMIGFGEKPTL
IALFLYALLPVFENTLTGLTTLPATVMDAARGSGMTGWQRLTKVELPLALPAILAGVRLS
AVISLSTATIGSTVAARTLGEVIIAGLQSNNLAFILQGGLIVAALAILIHAGFSALERSA
ARKTGH