Protein Info for Atu0126 in Agrobacterium fabrum C58

Annotation: membrane lipoprotein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 330 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF02608: Bmp" amino acids 35 to 309 (275 residues), 198.9 bits, see alignment E=5.1e-63

Best Hits

Swiss-Prot: 33% identical to TMPC_TREPA: Membrane lipoprotein TmpC (tmpC) from Treponema pallidum (strain Nichols)

KEGG orthology group: K07335, basic membrane protein A and related proteins (inferred from 99% identity to agr:AGROH133_03004)

Predicted SEED Role

"Predicted nucleoside ABC transporter, substrate-binding component" in subsystem D-ribose utilization or Deoxyribose and Deoxynucleoside Catabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CKN9 at UniProt or InterPro

Protein Sequence (330 amino acids)

>Atu0126 membrane lipoprotein (Agrobacterium fabrum C58)
MKKSLLTLFALAAMSASALAADIKPALVYGTGGKFDKSFNEAAAAGAEKFKAETGIDFRD
FEPTSDTQGEQAIRNFASKGFNPVVAVSFAWTSAMEKVAAEFPDTKFVIVDSVVELPNVR
SVVYKEHEGSYLVGLLAGMASKTGKVGFIGGMDIPLIRKFACGYAQGAKAANDKIEVFQN
MTGTTGAAWNDPVRGGELTKNQIDQGADVIYAAAGATGIGVLQTAADNKKFSIGVDSNQN
HLHPGSVLTSMVKRVDLAVYNAYKDAKDDKFTPGIVALGVKEDGVAYALDDNNKALITPE
MTAAVDKAKADIIAGTVKVHDYMADNSCPK