Protein Info for Atu0113 in Agrobacterium fabrum C58

Annotation: two component sensor kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 622 transmembrane" amino acids 19 to 40 (22 residues), see Phobius details amino acids 308 to 327 (20 residues), see Phobius details PF00512: HisKA" amino acids 395 to 460 (66 residues), 32.9 bits, see alignment E=8.3e-12 PF02518: HATPase_c" amino acids 506 to 613 (108 residues), 77.5 bits, see alignment E=1.6e-25 PF14501: HATPase_c_5" amino acids 509 to 602 (94 residues), 23 bits, see alignment E=9e-09

Best Hits

KEGG orthology group: K10125, two-component system, NtrC family, C4-dicarboxylate transport sensor histidine kinase DctB [EC: 2.7.13.3] (inferred from 100% identity to atu:Atu0113)

Predicted SEED Role

"MISCELLANEOUS; Not classified regulator"

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3

Use Curated BLAST to search for 2.7.13.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7D262 at UniProt or InterPro

Protein Sequence (622 amino acids)

>Atu0113 two component sensor kinase (Agrobacterium fabrum C58)
MESGFEACGRRGVSVKYRWILLMFLGLGLGYGAVTRGGGIIAESYFGEMSDQGHTTLRLA
VSALGGLLSRYEPLPALIADHDDIEELVAHPKDEALRQRANVYLKSINTLLESSDIYIIT
LDGETIAASNYDGPTSFVGENFSYRPYFQDAAKGLKSRFFALGTTSHKRGYYFSAPILFN
EEIKGVIVFKVDIEGIEASFGDGENRILVSDPEGIIFMTGTPQWLYSGLMPLTPERLART
EASRRYANATLTELPLKNGNFGSHQLMTIAQNDGDREYMVLSQPMQDAGWTVSVLMDTGS
LRTQVKTAMIAIILCLCLAAALIAAMLQRRRRLRERLTHQAEAQAELERRVEERTADLAR
VNQEIKHEIAERRQTEKQLRKMQNDLVQAGKLAALGQMSAALSHEFNQPLAAAKNYAENA
SLLVERGRLEEVTENLRRISGLIDRMASISKHLRNFARKPNEKTAAVGLETVIRDTLEIV
GPRLKAADAMLDIDLGPVPLAVKAGPVRLQQVLVNIISNAADAVEGREDRRISLQTVQHG
QAVSIFIRDHGPGVPAAISERIFDPFFTTKGVGRGLGLGLSISYNIIKDFGGQLRVKNHE
ESGAEFEIELPAAAWRTEAAAE