Protein Info for Atu0098 in Agrobacterium fabrum C58
Annotation: mutT/nudix family protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K03426, NAD+ diphosphatase [EC: 3.6.1.22] (inferred from 100% identity to atu:Atu0098)Predicted SEED Role
"NADH pyrophosphatase (EC 3.6.1.22)" in subsystem Nudix proteins (nucleoside triphosphate hydrolases) (EC 3.6.1.22)
MetaCyc Pathways
- NAD salvage pathway I (PNC VI cycle) (6/7 steps found)
- NAD salvage pathway II (PNC IV cycle) (4/5 steps found)
- NAD salvage pathway III (to nicotinamide riboside) (2/3 steps found)
- NAD salvage (plants) (6/11 steps found)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 3.6.1.22
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A9CKP9 at UniProt or InterPro
Protein Sequence (320 amino acids)
>Atu0098 mutT/nudix family protein (Agrobacterium fabrum C58) MMSMKIFETTAPHPEASLLTAFSKNALDRFAEKRTEECVAEALKVDGTHIFAFSGNRLVL KHDEQVIDPLFSAYELAELQPDFDNAVLLGYRETGEPRIAVPVAVAEDQLASHYKLADAR TLYRDHLLDEELLSEVAQAVSLTHWNADNRFCGRCGGTMEQRIGGYKRICASCSHTIFPR TDPVVIMMTIDIERDLCLLGRGAHFASGMYSCLAGFVEPGETIEQAVRRETHEESGVEIG RVRYHASQPWPMPHTLMIGCYAEALSSDIARDEIELEDCRWFTREEVAKMLEAPAGEGFS APPIGAIAHRLMRDWVEWPE