Protein Info for Atu0096 in Agrobacterium fabrum C58

Annotation: DNA polymerase III, tau subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 624 TIGR02397: DNA polymerase III, subunit gamma and tau" amino acids 18 to 378 (361 residues), 404.5 bits, see alignment E=2.2e-125 PF13177: DNA_pol3_delta2" amino acids 37 to 198 (162 residues), 120.8 bits, see alignment E=2e-38 PF13401: AAA_22" amino acids 55 to 177 (123 residues), 31.3 bits, see alignment E=8.4e-11 PF00004: AAA" amino acids 58 to 192 (135 residues), 42.4 bits, see alignment E=3.2e-14 PF22608: DNAX_ATPase_lid" amino acids 208 to 250 (43 residues), 63.8 bits, see alignment 3.5e-21 PF12169: DNA_pol3_gamma3" amino acids 252 to 394 (143 residues), 180.5 bits, see alignment E=5.5e-57 PF12362: DUF3646" amino acids 478 to 590 (113 residues), 129.6 bits, see alignment E=2.3e-41

Best Hits

KEGG orthology group: K02343, DNA polymerase III subunit gamma/tau [EC: 2.7.7.7] (inferred from 100% identity to atu:Atu0096)

Predicted SEED Role

"DNA polymerase III subunits gamma and tau (EC 2.7.7.7)" in subsystem DNA-replication (EC 2.7.7.7)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.7

Use Curated BLAST to search for 2.7.7.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CKQ1 at UniProt or InterPro

Protein Sequence (624 amino acids)

>Atu0096 DNA polymerase III, tau subunit (Agrobacterium fabrum C58)
MSDTVPPKSSESQVGTGYRVLARKYRPKDFSDLMVGQEPMVRTLTNAFETGRIAQAYMLT
GVRGVGKTTTARILARALNYKTDTIDKPTIDLRIPGEHCQAIMEGRHVDVIEMDAASHTG
IDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPEHVKFIFATTEIR
KVPITVLSRCQRFDLRRISAADLVGLFTAIAGKEGFEAEPQALSMIARAAEGSARDGLSL
LDQAIAHGGGRVEAEAVRGMLGLADRARIVDLFQHVVKGDVAAALSEFNGQYEAGANPVV
VLNDLADFTHLVTRMKYVPDAAEDPSLSEIERTRGAEFAETIAVTALSRIWQMLLKGIPE
TENASRPAGAAEMVLIRLSHAANLPAPEDAARRLLELSSADGSYTNGGPSGGGNGGGARA
YSSAQTVAAARPAEFAAPRQAGPQPSTMLRAVPDSRPQEMQVAAPKTEERPEPKVPVNSL
QDIADLCQKNRDPVMRAKVRNFVRLVRLEPGRLDMRLGEGAPGSLPGELGVKLKEWTGIH
WIVSLSKEQGEPTLVEAEGNARDARLVDARQDPDVAAILAQFPGAKITDVRIRAAIQDEA
EDITPPSVAESSEGDILPGDDIEF