Protein Info for AMB_RS23945 in Magnetospirillum magneticum AMB-1

Annotation: DUF3365 domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 767 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details transmembrane" amino acids 201 to 220 (20 residues), see Phobius details PF11845: Tll0287-like" amino acids 24 to 184 (161 residues), 74 bits, see alignment E=7.8e-24 PF00989: PAS" amino acids 246 to 341 (96 residues), 39.6 bits, see alignment E=2.2e-13 TIGR00229: PAS domain S-box protein" amino acids 247 to 351 (105 residues), 52.5 bits, see alignment E=2.7e-18 PF13426: PAS_9" amino acids 251 to 345 (95 residues), 48.7 bits, see alignment E=3.6e-16 PF08447: PAS_3" amino acids 259 to 335 (77 residues), 28.5 bits, see alignment E=6.7e-10 PF13185: GAF_2" amino acids 375 to 521 (147 residues), 71.7 bits, see alignment E=3.4e-23 PF01590: GAF" amino acids 378 to 520 (143 residues), 36.2 bits, see alignment E=3.7e-12 PF00512: HisKA" amino acids 550 to 615 (66 residues), 46.9 bits, see alignment E=1e-15 PF02518: HATPase_c" amino acids 658 to 766 (109 residues), 100 bits, see alignment E=5.1e-32

Best Hits

KEGG orthology group: None (inferred from 54% identity to mag:amb3689)

Predicted SEED Role

"Phytochrome, two-component sensor histidine kinase (EC 2.7.3.-); Cyanobacterial phytochrome B" (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.3.-

Use Curated BLAST to search for 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (767 amino acids)

>AMB_RS23945 DUF3365 domain-containing protein (Magnetospirillum magneticum AMB-1)
MVGSAALWTAAVLLSFWMAAENERQQAVRLAVQEARTSVQTDIGFRHWVASHGGVYVAPD
AQTSPNPYLNVPDRDVVTTNGKHLTLMNPAYVLRQLMQSGFVAKGRITSMKPLNPENAPD
EWEHQALLLLEQGETEVTEKVLSNGKAAVRVMAPIRVEQSCLTCHGDQGYKVGDLRGGID
VTIPLEKSNEIASTEIKRLALNHAIFWALVMSGIGLMWGIGKSHIRKHELLTIRHLITQF
SRDRAEEPVYWINESGLISYVNDSACSLLGYDEREMLNLHASELNPDHPREKWAEHWRSL
KEERFLRFDATLKRKDGSTLPVEISANYLSHEGQEFDVAFVRDMSSHKEATVKIAHLTDI
YAALSQTNKAIIRSKSRQELFDAIVRISVDFGHFRMAWIGVVDDASRAIVPVAWAGEGIA
YLDGLKVSADADSPYGQGPSGQCIRAGEHRVAENFFGTQITAPWQKRAAFFNFNSSAAFP
LKNQGKTIGTLSLYSDVPEFFTDDLIELLTEMTDEISFALDRMDLEASHRQHEAEQKELV
ERLMASNTELERFAYVASHDLQEPLRTIVSFAQLLDRHLGDKLPPEDRENFEFVVGAAKR
MGLLINDLLAFSRVSAKGVSFSRISLTAACSAAQDNLREVISQNHAEITVGQLPEVIGDD
VQLMQVFQNLVGNAVKFRHPDRKPQISIDAEQKDGKWQIAVRDNGIGIADTTQDIFEIFR
RLHAGNQYPGSGVGLAICKRIITQHGGQIWVESEPGHGATFRFTVPV