Protein Info for AMB_RS21065 in Magnetospirillum magneticum AMB-1

Annotation: double-strand break repair helicase AddA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1154 transmembrane" amino acids 343 to 360 (18 residues), see Phobius details TIGR02784: double-strand break repair helicase AddA" amino acids 13 to 1139 (1127 residues), 1221.9 bits, see alignment E=0 PF00580: UvrD-helicase" amino acids 14 to 163 (150 residues), 91.6 bits, see alignment E=1.8e-29 amino acids 355 to 468 (114 residues), 72.9 bits, see alignment E=8.8e-24 PF13245: AAA_19" amino acids 22 to 86 (65 residues), 29.5 bits, see alignment 1.9e-10 PF13361: UvrD_C" amino acids 589 to 874 (286 residues), 53.7 bits, see alignment E=5.8e-18 PF12705: PDDEXK_1" amino acids 985 to 1118 (134 residues), 39.3 bits, see alignment E=1.9e-13

Best Hits

KEGG orthology group: None (inferred from 100% identity to mag:amb4162)

Predicted SEED Role

"FIG061771: ATP-dependent nuclease subunit A"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2VZK9 at UniProt or InterPro

Protein Sequence (1154 amino acids)

>AMB_RS21065 double-strand break repair helicase AddA (Magnetospirillum magneticum AMB-1)
MTDGSVLSFDADQRQRRAADPTASVWVAASAGTGKTKVLTDRVLTLLLAGTPPHKILCLT
FTKAAAAEMSNRIAGRLGQWATAHDSDLADDLGRLLGRAPSPGEMTGARRLFAALLDAPG
GMHMETIHAFCQSLLRRFPLEAGIAPHFQVMDDRDAGELLEAAKLEILSQARMGDGALGG
ALALVTSRVHETAFPELMGELTAERGRLERLFERHGGVEGALAALRTRLGLEAGDTPDSL
LAWATDEAHFQGEGLREAVAALLTGSDSDRKRGEAMARWLADPAGRENGFAGWCAQFLTA
EGGIRKTLATKAVREGFPGVEDCLLAEAERLYRLTERLRAARIAEATGALLTLGGALLAS
YRRAKTHRALMDYDDLILGARDLLARPGVAPWVLYKLDGGIDHVLIDEAQDTNPDQWAVV
EKLTEEFFAGRGARETLRTVFAVGDAKQSIYSFQRADPREFERMREAFATHVPAAGGKWE
VVDLNLSFRSAPAVLEAVNAVFAPGRPGRDGVAGDEDITHLPHRGGQAGRVEVWPVVEPR
PADELPAWKPPVERIRGDSPRTRLARLMAARIRAMIDGEVLESKGRPVRAGDVLVLVRRR
GGFVEDLVRELKSRKVEVAGADRMVLTEQMAVMDLMALGNFLLLPEDDLTLATVLKGPLV
GLGEDQLFTLAHHRGKDVGLWEALRQGVADEGGVFEAAFRRLSELLAQADRVSPHTLYAR
VLGPLGGRRRLLARLGLEAEDSIDEFMSLTLAFERAHPPSLQGFLHWLEAGALEIKRDLE
QAGRDAVRIMTVHGSKGLQAPIVFLPDTMQVPTRSPRLLWLGEGEGELPAWPPRAEDMDS
VCRQGADARKQSREREYRRLLYVAMTRAEDRLVVCGWRGLKAAPETCWHALVQCALAPTA
AAFDDPFLAKAAETAEGPVLVLANAQTAPPEKEKGAGPGAGQSSPLPDWALLSAEPEPIP
PRPLAPSRPEGEEPTVRSPLAEMDGKPRWQRGKLIHRLLQTVPDLPPPDRSRAMLRFLAR
PAWGLETPEQLAIANEVSDILDHPGLAGLFAPGSRAEVPLVGRIGDRVVSGRVDRLAVSD
TEVVIADYKTNRRPPATPDEVPELYVRQMAAYRLALACIYPSHRVRCVLVWTDGPLLTEI
PSARLDDALAGLVE