Protein Info for AMB_RS19825 in Magnetospirillum magneticum AMB-1

Annotation: signal transduction histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 547 transmembrane" amino acids 31 to 54 (24 residues), see Phobius details amino acids 310 to 328 (19 residues), see Phobius details PF07568: HisKA_2" amino acids 361 to 436 (76 residues), 88.3 bits, see alignment E=5.9e-29 PF07536: HWE_HK" amino acids 361 to 416 (56 residues), 29 bits, see alignment 2.9e-10 PF13581: HATPase_c_2" amino acids 458 to 544 (87 residues), 29.5 bits, see alignment E=1.3e-10 PF02518: HATPase_c" amino acids 460 to 546 (87 residues), 44.5 bits, see alignment E=3.9e-15

Best Hits

KEGG orthology group: None (inferred from 100% identity to mag:amb3917)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2W0A4 at UniProt or InterPro

Protein Sequence (547 amino acids)

>AMB_RS19825 signal transduction histidine kinase (Magnetospirillum magneticum AMB-1)
MNGGRVDISQSSRLDKPSEAVQSSRLPRPRLLLAMIVAIAVLGGMAGLATLTWFDHQATL
DDWSANLRLSAHLVESHTRAAHGTVHAHLGTVIGRVGGKPLAALRSSRQDRDWLETLLTE
LPHGVAIAIHDERGDPVLVTDRLGLFSANASHRDYFILAMGQPGRTVMSAVVPGRGDQGR
AIIFSRAILDAAGRPQGVAEIALKTDYFIEFYRSLQSEPGAIFLVSRLDGGLVARYPLPD
ATFTRFDTSKHPFTEFAKGQSGIYRSTSVVDGIERLVAYRNLADLEMVVTSGIPTKVVFR
EWTVRSRRNALLFVTAMVLMLVLAAITSESLRHEARLLATGERRTRDLTTALAEKDVLFQ
EVHHRVKNNLQVISSLLTMQSLHVTDEKVKETLKDALDRIHSMGLVHQTLYERNLASNVD
LGTYFGKLAEALAGSYASSPGGVTVEVEVEGTLDLERAVPLGMLANEVLSNAMKHAFSDG
RRGTIWVTLVREAGEWHFTVRDNGVGMPDKPGRGIGIGLIRALSRQLGGRSHIFVDEGTV
VSVTFPA