Protein Info for AMB_RS19740 in Magnetospirillum magneticum AMB-1

Annotation: protein translocase subunit SecA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 901 PF07517: SecA_DEAD" amino acids 7 to 387 (381 residues), 438.8 bits, see alignment E=2.7e-135 TIGR00963: preprotein translocase, SecA subunit" amino acids 28 to 807 (780 residues), 1116.9 bits, see alignment E=0 PF00270: DEAD" amino acids 100 to 218 (119 residues), 24.8 bits, see alignment E=4.9e-09 PF01043: SecA_PP_bind" amino acids 232 to 344 (113 residues), 137.7 bits, see alignment E=7.3e-44 PF21090: P-loop_SecA" amino acids 404 to 607 (204 residues), 313 bits, see alignment E=2.7e-97 PF07516: SecA_SW" amino acids 609 to 821 (213 residues), 233.3 bits, see alignment E=8.7e-73 PF02810: SEC-C" amino acids 882 to 899 (18 residues), 39.6 bits, see alignment (E = 1.1e-13)

Best Hits

Swiss-Prot: 67% identical to SECA_ACICJ: Protein translocase subunit SecA (secA) from Acidiphilium cryptum (strain JF-5)

KEGG orthology group: K03070, preprotein translocase subunit SecA (inferred from 72% identity to azl:AZL_025630)

Predicted SEED Role

"Protein export cytoplasm protein SecA ATPase RNA helicase (TC 3.A.5.1.1)" (TC 3.A.5.1.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2W0C1 at UniProt or InterPro

Protein Sequence (901 amino acids)

>AMB_RS19740 protein translocase subunit SecA (Magnetospirillum magneticum AMB-1)
MFGALARRIFGTANDRVLKPLKKHVEAVNALEPAFEKLSDDELRAKTAEFRARLESGTEL
NDLMAEAFATVREAAKRTLGQRHFDVQLLGGMVLHQGRISEMKTGEGKTLVATLPVYLNA
LTAKGVHVVTVNDYLAKRDSEWMGQVYRFLGLTVGVIVHGMDDLERQQAYACDVTYGTNN
ELGFDYLRDNMKFRLEEMVQRPFNYAIVDEVDSILVDEARTPLIISGPTEDNSDLYRLVD
KLMPSLVAEDFEKDEKVRAVTLTDRGTEHVEEMLRTADLMKGTLYDIGNVSLVHHVNQAL
RAHKLFTRDVDYIVKNDKVIIIDEFTGRMMEGRRYSEGLHQALEAKEGVTIQNENQTLAS
ITFQNYFRLYPKLAGMTGTAMTEAGEFAEIYNLEVVEIPTNLAVSRTDHDDEVYRTAKEK
YEAIVTLIEECRGRMQPVLVGTTSIEKSELLSDMLKKKKIPHQVLNARYHEQEAYIVAQA
GVPGGVTIATNMAGRGTDIQLGGNLDMRTRMELADVTDPAERVKRIEGLKAEIEVNKQKV
RESGGLYVVGSERHESRRIDNQLRGRSGRQGDPGASKFFLSLEDDLMRIFGSQRMDGMLQ
KLGLKDGEAIVHPWINKALEKAQQKVEARNFDIRKNLLKFDDVMNDQRKVIYEQRKDLMS
ADDVSEEIVAFRHEVIAEMVARCIPERAYADQWDVAALHEEVLRVFNLDLPIAEWGKEEG
IADQEIRDRITDHADRKAAAKVAEYTPDTMRMVEKSLLLQILDQAWKEHLLQLDHLRQGI
SLRAYAQRDPLNEYKREAFNMFEQMLLDLRERVTSVLAHVQLRFSSEEEAEQALEPQRPA
RTQETREDPAFSSGGSGAPFALAQRNTAVDPNDPATWAATPRNAPCPCGSGKKFKHCHGA
A