Protein Info for AMB_RS19620 in Magnetospirillum magneticum AMB-1

Annotation: HAMP domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1186 transmembrane" amino acids 20 to 40 (21 residues), see Phobius details amino acids 195 to 215 (21 residues), see Phobius details PF12729: 4HB_MCP_1" amino acids 16 to 184 (169 residues), 57.8 bits, see alignment E=3.2e-19 PF00672: HAMP" amino acids 217 to 265 (49 residues), 26 bits, see alignment (E = 2.9e-09) PF13185: GAF_2" amino acids 292 to 419 (128 residues), 43.7 bits, see alignment E=1e-14 PF00512: HisKA" amino acids 527 to 594 (68 residues), 58.9 bits, see alignment 1.2e-19 PF02518: HATPase_c" amino acids 642 to 753 (112 residues), 95 bits, see alignment E=1.2e-30 PF00072: Response_reg" amino acids 794 to 899 (106 residues), 57.3 bits, see alignment E=5e-19 amino acids 917 to 1002 (86 residues), 35.9 bits, see alignment 2.3e-12 amino acids 1062 to 1172 (111 residues), 95 bits, see alignment E=1e-30

Best Hits

KEGG orthology group: None (inferred from 100% identity to mag:amb3878)

Predicted SEED Role

"Signal transduction histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2W0E3 at UniProt or InterPro

Protein Sequence (1186 amino acids)

>AMB_RS19620 HAMP domain-containing protein (Magnetospirillum magneticum AMB-1)
MSWPLEGGSVRSSQVRIVTRLTAGFAAVLLLTVIMAGMAARTMLSIADLAGELYTHPFAV
TNALMQIESQVNAMRADMLLMIYNRSAADVARLSGSVAIKESEMAASLEVVRKQYLGNPE
DVKRLSDELAQWKVVRDQNIRFCQEGEYDKASENSRKYGSPQIVILRRHIAGIYAFAQDK
AAEFRNRITAQRDQAVRDIALTLLALLILGTLLARTITRSIVIPLGELRDVMHRLAKGEL
DAHVPNQSRVTEVSRMALAVEVFKQAALRLERDRWIKDNLARLSPALQQTDSIAEFGTTA
LDFLVPLSGAGVATFNARTGGNRFMRVAGWGMPRASETLGLDSFAPGEGVAGEAARSGSP
ILIEAPPESWLHVTSATGAAAPAAIFVMPVMSRGTALAVLEFASFTAFDDSQKALLEAAL
PMLALNIEILERNLRTLDLLEESQTQAEELKASEEELRAQGEALQVANEELRVSEEELKV
QQEALQTANEELRLKSEALEERGKALEDARAEADRRALDVEQASRYKSEFLANMSHELRT
PLNSVLILARDLADNDTGNMSDDQVESARVIHESGTHLLALINDVLDLSKVEAGKMTLDP
VTIAIADLVQVIRGRFAPVATDKGLGFQVEVDPDLPRSLKADRGKIEQIANNLVSNAIKF
TSEGGVTVRLSLTGDGHVLALSVADTGIGIAPQDRQRVFAAFEQADSGTSRQFGGTGLGL
TISRKLARLMGGDITLDANGDKGSVFTLLLPLAGTTQLPAPRCAPEPRPASARPSPPAAE
AIEETPKAEGKLLLVIEDDPIFRRVVCDMAQAKGFATATAGDGKTGLELARLRRPSGVVL
DIGLPDMSGWEVIEALKLQPETRDIPVHVMSAGDEPGRAARLGTVGHLTKPVSREQINGA
FEVLLRARRADGRRRLLLVDGDEASRATIGETLVGLDLDITVAETGQVALEHLAAGPFDC
MVLDLALSDMAGGEFLERAERIGSGLPPVIVYSSQELSQDQTLRIREFTDSIVIKGSRSS
ERLLDEVGLFLHAVDAKKSGKAKPSPVAAEPVDAILAGRTALLVDDDMRNAFALSKVLRA
RGLKVLIAQDGAKALSQLQSRADVDLVLMDIMMPGMDGYQTMGEIRKDPRFAHLPIIALT
AKAMAGDRDRCLAAGADDYLTKPVDVERLRQVMALLIRRGDHAQPS