Protein Info for AMB_RS19470 in Magnetospirillum magneticum AMB-1

Annotation: putative lipid II flippase FtsW

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 376 transmembrane" amino acids 23 to 42 (20 residues), see Phobius details amino acids 62 to 80 (19 residues), see Phobius details amino acids 86 to 106 (21 residues), see Phobius details amino acids 127 to 143 (17 residues), see Phobius details amino acids 149 to 168 (20 residues), see Phobius details amino acids 188 to 213 (26 residues), see Phobius details amino acids 277 to 294 (18 residues), see Phobius details amino acids 306 to 326 (21 residues), see Phobius details amino acids 343 to 364 (22 residues), see Phobius details TIGR02614: cell division protein FtsW" amino acids 21 to 367 (347 residues), 340.3 bits, see alignment E=6.5e-106 PF01098: FTSW_RODA_SPOVE" amino acids 25 to 368 (344 residues), 259 bits, see alignment E=3.5e-81

Best Hits

Swiss-Prot: 48% identical to FTSW_CAUVN: Probable peptidoglycan glycosyltransferase FtsW (ftsW) from Caulobacter vibrioides (strain NA1000 / CB15N)

KEGG orthology group: K03588, cell division protein FtsW (inferred from 100% identity to mag:amb3847)

Predicted SEED Role

"Cell division protein FtsW" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2W0H4 at UniProt or InterPro

Protein Sequence (376 amino acids)

>AMB_RS19470 putative lipid II flippase FtsW (Magnetospirillum magneticum AMB-1)
MSVTFGRTDTSVLGRWWWTVDRWTIAALFLLVAVGAILTMAASPAVAERIGAQSFHFVRR
QFMFLAPAIIIMLGVSLLAPKQVRRMAVIGLLGSILLLAVVPVLGGEIKGAKRWLNLAGI
SIQPSEFVKPMFAVVSAWMFASARLDPAFPGRIIATALFGLVAALLLIQPDVGQTAILTA
IWGTQFFLAGLPLILVVGLGLAAPIGIVGAYYVFPHVQARFDKFLDPSGSGAYQVTTALN
AFKNGGLFGKGPGEGRVKLVLPDAHTDFILAVGGEEFGVLMCLFVVMLFAFIVLRGFSRI
HKDDNLFVVLATAGLLVQFGLQAIVNMASTLRMMPAKGMTLPFISYGGSSMVALALGMGM
VLALTRTRYGREGMEA