Protein Info for AMB_RS18500 in Magnetospirillum magneticum AMB-1

Annotation: two-component sensor histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 405 TIGR00229: PAS domain S-box protein" amino acids 42 to 165 (124 residues), 34.2 bits, see alignment E=1.2e-12 PF00512: HisKA" amino acids 186 to 251 (66 residues), 37.4 bits, see alignment E=2.2e-13 PF02518: HATPase_c" amino acids 295 to 404 (110 residues), 99.9 bits, see alignment E=1.2e-32

Best Hits

KEGG orthology group: None (inferred from 100% identity to mag:amb3655)

Predicted SEED Role

"Phytochrome, two-component sensor histidine kinase (EC 2.7.3.-); Cyanobacterial phytochrome B" (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.3.-

Use Curated BLAST to search for 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2W116 at UniProt or InterPro

Protein Sequence (405 amino acids)

>AMB_RS18500 two-component sensor histidine kinase (Magnetospirillum magneticum AMB-1)
MNQHPGDETPPSPEHLLHELRVHQIELEMQNDELRRAQLALEESRDRYVDLFEFAPVGYL
ILSRIGVITQINLTGAALLGVERAGVIAQRFDAFVAGTDHDRWHRHLAHALHHTGRHECE
LVLLRADGRNFNGHLDCQLQEQDAAPVLRVALTDITVRKTAEAELADTREALLRANERLR
ASNRDLEQFAYVASHDLQEPLRMVVSYGQLLERKYHDRLDDDAHTFIDFMVEGGARMQAM
VTDLLEFSRVDRMGGEREPFDSGKAVEEAKFSLSQAIAESGAEIGHAGLPEIVYDSHQFV
RLMQNLIGNALKYHDPGRPPKVTVTARRDGHQWEFSVSDNGIGIDPAYFEQIFAVFRRLH
TRDRYGGTGIGLAVCKKIVEHHGGRIWVESTPGAGSAFFFTAPDP