Protein Info for AMB_RS18265 in Magnetospirillum magneticum AMB-1

Annotation: ATP-dependent DNA helicase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 920 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details transmembrane" amino acids 745 to 758 (14 residues), see Phobius details PF13307: Helicase_C_2" amino acids 744 to 883 (140 residues), 74 bits, see alignment E=8e-25

Best Hits

KEGG orthology group: None (inferred from 100% identity to mag:amb3608)

Predicted SEED Role

"DinG family ATP-dependent helicase YoaA" in subsystem DNA repair, bacterial DinG and relatives

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2W163 at UniProt or InterPro

Protein Sequence (920 amino acids)

>AMB_RS18265 ATP-dependent DNA helicase (Magnetospirillum magneticum AMB-1)
MSAPSRILLPHVPVLVAGIRGAVALEPDGEFRRLSRSEAARYARNESPLVCHGPAVAARL
GLDDFLRLDILELFAFVRPARFCLPTPRGLADAMGLPHPADLEDEAEALMNAVRRLLEEL
SSRTNADTAAKAVDTRGLAWMMARGGWGWGNAVLAALGVQGDSGRGGGALRVWDRLPEWS
EYAPEPPPGNIPVDPTETRQRLAQMLGEGAEQRPTQADYASAVSRAFLPREAEGQPHLVL
AEAGTGTGKTLGYIAPAGLWAEKNGAPVWISTHTRNLQRQLDGELDRLFPNAGDKARKVV
IRKGRENYACLLNYEEMVSRNRNQDAPAVGLMARWLLATRDGDMVGGDFPGWLTEVLGRA
RTLGIADRRGECIFSACPHYRKCFIERAVRRARRADIVVANHALVMIQAALGGLDDGAQP
TRLVFDEGHHVFDAADAAFSAHLTGLEAAEVRRWILGPEGEAVSRSRARGLHRRAEDLVG
GSEEAIAALDGALAAARALPGPGWMVRISEGEPQGPAEAFLGLLRRQVYARAAHPDSPYS
LETETTAPLEGLPEAAGALAAALGRIALPLQVLSKSLSALLDDEAAELESATRSRIEGIC
RSIERRVLMPLAGWKGMLDGVVQGGGVVERQYIDWFSVDRIDGRDYDAGMHRHWIDPTRP
FAKAVVEPAHGVVITSATLKDGSGDVETDWRAAERRTGALHLDSDPLRAEVASPFDYPTR
TKVLIVTDVRKDDMDQVGAAYRELFLAANGGALGLFTAISRLKAVHKRISAPLEDAGLPL
LAQHLDNMDTSTLVDIFRAEEHSCLLGTDAVRDGVDVPGRSLHLIVFDRVPWPRPDILHK
ARRAEFGGRAYDDMITRLRLKQAFGRLVRRADDRGVFVLLDPMMPSRLFGAFPPGVEPVK
VGLAEAVRQCRQLLAATADA