Protein Info for AMB_RS17075 in Magnetospirillum magneticum AMB-1

Annotation: FAD-dependent oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 651 PF14691: Fer4_20" amino acids 49 to 137 (89 residues), 44.7 bits, see alignment E=6.4e-15 PF03486: HI0933_like" amino acids 150 to 184 (35 residues), 25.7 bits, see alignment (E = 3e-09) PF01266: DAO" amino acids 150 to 184 (35 residues), 31.6 bits, see alignment (E = 8.2e-11) PF07992: Pyr_redox_2" amino acids 150 to 467 (318 residues), 81.8 bits, see alignment E=3.6e-26 PF00890: FAD_binding_2" amino acids 151 to 185 (35 residues), 26 bits, see alignment (E = 3.3e-09) PF12831: FAD_oxidored" amino acids 151 to 187 (37 residues), 30.8 bits, see alignment 1.2e-10 PF13450: NAD_binding_8" amino acids 153 to 188 (36 residues), 39.9 bits, see alignment 2.6e-13 PF01593: Amino_oxidase" amino acids 159 to 212 (54 residues), 23.1 bits, see alignment 2.6e-08 PF13187: Fer4_9" amino acids 594 to 644 (51 residues), 29.2 bits, see alignment 4.5e-10 PF12838: Fer4_7" amino acids 594 to 643 (50 residues), 33.8 bits, see alignment 2.3e-11 PF00037: Fer4" amino acids 624 to 643 (20 residues), 23.1 bits, see alignment (E = 3e-08)

Best Hits

KEGG orthology group: None (inferred from 100% identity to mag:amb3375)

MetaCyc: 62% identical to DsrL (Allochromatium vinosum)

Predicted SEED Role

"Protein similar to glutamate synthase [NADPH] small chain, clustered with sulfite reductase" in subsystem Sulfate reduction-associated complexes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2W1U6 at UniProt or InterPro

Protein Sequence (651 amino acids)

>AMB_RS17075 FAD-dependent oxidoreductase (Magnetospirillum magneticum AMB-1)
MAAKTSAETTTEGRNFRRYQDGDFTPKHWQEEIFKAGWSHKCPTYVLRTPPCSGSCPSGH
DIRGWLDIVRGVEKPPAGMAWQEYAFRRMVEANPFPAVMGRVCPAPCESGCNRNMVEEHV
GINSVEHHIGDWAIANKLTFPKPEHETGKHVAVVGGGPAGLSAAYQLRRQGHAVTLFEEK
AELGGYVRYGIPGYRTPREVLDSEIGRIIDMGITVRTQCRIGTDITVSELEEKYDAIFWG
IGTHAGRGLPIPGWKDTVNCVSGVAFLKAFNEGRLQHVPGRIIVVGGGDTSIDVASVARR
LGHIDTVSEQDRADNVILGHVAHDVAATARREGANVTLTSLFPVEKMFAAQREIDDAKRE
GVDIRGGIMPLEVILGADGRATGLKLCQCTMEGMIPKPVEGTEFVLDADLVVSAIGQSGD
LADLPEMDNGKGFINADKAYRVPGKPKHFVGGDVVKPHLLTTAIGHGRVASAGIAEFLDH
GDVAKRPKVDVHHFNLLAKLHESNLDPAPYQPGPVRGTFEAKFAVHNFENRSAEQIIPHD
DLFLGHFTRTARHHRHEVHIDADKVIGNFDERLLTLTDQEVIDEAKRCMSCGLCFECDNC
VVFCPQTAVSRVKKSERTTGRYVETDYAKCIGCHICKDVCPTGYIQMGLGE