Protein Info for AMB_RS16370 in Magnetospirillum magneticum AMB-1

Annotation: two-component sensor histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 456 transmembrane" amino acids 12 to 33 (22 residues), see Phobius details amino acids 130 to 142 (13 residues), see Phobius details amino acids 170 to 189 (20 residues), see Phobius details PF08521: 2CSK_N" amino acids 21 to 160 (140 residues), 26 bits, see alignment E=1.7e-09 PF00672: HAMP" amino acids 188 to 239 (52 residues), 28.2 bits, see alignment 3.8e-10 PF00512: HisKA" amino acids 245 to 301 (57 residues), 44.6 bits, see alignment 2.5e-15 PF02518: HATPase_c" amino acids 349 to 450 (102 residues), 88.7 bits, see alignment E=7.4e-29

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (456 amino acids)

>AMB_RS16370 two-component sensor histidine kinase (Magnetospirillum magneticum AMB-1)
MIRQPPAILWRIVVRLSLTTLVAIVMAYSWLWWKYHSVTEVMRDTYLIEQAIAIRNQVTV
RPDGRITVDLPPIQTASYAESEGSLRFAVRLRSSGAILAQAGEPVGPAPEMGDGPRLYRS
NPDGPGPVLMFGAAVLLTSPAGELVIQVEESGSDFDAMTRSLVERFAKEGGWLGAPFLLA
MLLVSLVTIRNSLLPLKRLSEQAAAIGPASTDIRLPEAQVPREILPLVHAVNSALDRIEA
GFRIQRDFTADAAHELRTPLAVLRAHVETLPDPAIREALVRDVDSMTRLIAQLLAVARAE
ALTIAMDEQADLNAIAVDVGTFLAPMALRQRRMIEVIEAPRPCLVTANAEAVFNAVRNLV
ENALTHAPSDTTVTVRVEAPASLLVEDCGPGVPAELRERIFQRFWRAERRKSGSGLGLAI
VREIMLAHGGRVEVGDRPGGGAVFSLHFPDQGAQRR